Navigation Links
Accelerated bone turnover remains after weight loss
Date:7/28/2008

COLUMBIA, Mo. When a person is losing a significant amount of weight, they expect to notice changes in their body. However, they may overlook changes happening in their bones. During weight loss through calorie-restricted diets, bones are being remodeled - breaking down old bone and forming new bone - at an accelerated rate. At the same time, bone density is decreasing, causing increased fragility. In a new study, a University of Missouri researcher and collaborators at the University of Kansas found that the potentially harmful effects of weight loss on bone persist during weight maintenance following moderate weight loss.

Researchers examined protein markers of bone breakdown and formation in 37 obese, middle-aged adults who lost 20 percent of their body weight through a severe calorie-restricted diet. Protein markers, which are released during bone breakdown and formation, are used as indirect indicators of bone remodeling. During the 3-month weight-loss phase, bone remodeling was elevated, and bone formation and breakdown were imbalanced as a result of a low energy intake. After weight loss phase, bone remodeling remained elevated during the 9-month weight maintenance phase, but bone formation and breakdown appeared to be balanced.

"When people increased their calorie intake after weight loss, the bone remodeling markers did not respond and remained above what they were before weight loss," said Pam Hinton, associate professor of nutritional sciences in the MU College of Human Environmental Sciences. "However unlike the weight loss phase, it appeared that bone breakdown and bone formation were balanced. Rapid rates of bone remodeling, regardless of the balance of breakdown and formation, can increase bone fragility."

Hinton found that a greater reduction in body weight resulted in a greater increase in bone breakdown. Having a low-carbohydrate or a low-fat diet during the weight maintenance phase had no effect on bone rem
'/>"/>

Contact: Kelsey Jackson
JacksonKN@missouri.edu
573-882-8353
University of Missouri-Columbia
Source:Eurekalert

Page: 1 2

Related biology news :

1. New technique determines the number of fat cells remains constant in all body types
2. Chesapeake Bay ecosystem health remains poor, but slightly improved in 2007
3. Video released of rapid Alzheimers improvement after new immune-based treatment
4. Dioxin risk in soil and plant tissues after long-term biosolids application
5. Children born from frozen embryos weigh more and do better than those born after fresh transfer
6. Children born after donor insemination should be told as soon as possible about their conception
7. Resuscitation technique after brain injury may do more harm than good
8. Dwarf cloud rat rediscovered after 112 years
9. Pregnancy is possible after cancer treatment
10. Many African-Americans have a gene that prolongs life after heart failure
11. Breast cancers behave differently before and after the age of 70
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/5/2015)... OXFORD, Conn. , Jan. 28, 2015 ... ("NXT-ID" or the "Company"), a biometric authentication company focused ... present at the upcoming RedChip Global Online CEO Conference ... Gino Pereira , CEO of ... discussing its lead product, the Wocket smart wallet and ...
(Date:2/5/2015)...  It is gratifying to see that the Obama ... science as a means to better understand human biology, ... was honored to participate in today,s White House event ... Since the 1980s my teams have been ... sequenced genome of a free living organism, the first ...
(Date:1/22/2015)... Research and Markets ( http://www.researchandmarkets.com/research/4trb7t/biometrics_a ) has announced ... Overview" report to their offering. , ... an individual is who she/he is claiming to be, and ... person,s unique physical characteristics, such as fingerprint, hand or palm ...
Breaking Biology News(10 mins):CEO of NXT-ID, Inc. to Discuss Company's Biometric Technologies at RedChip Online Conference January 29th 2CEO of NXT-ID, Inc. to Discuss Company's Biometric Technologies at RedChip Online Conference January 29th 3J. Craig Venter, Ph.D., Co-Founder and CEO, Human Longevity, Inc. (HLI) Participates in White House Precision Medicine Event 2Biometrics - A Global Market Overview 2Biometrics - A Global Market Overview 3
... of developing bipolar disorder depends in part on the combined, ... the brain, none of which is powerful enough to cause ... targeting the enzyme produced by one of these genes could ... research was conducted by scientists at the National Institutes of ...
... studied the molecular basis of memory storage, trying to ... stores genetic memory. In an important study published this ... report for the first time that memory storage can ... rat hippocampus by manipulating a so-called "memory molecule," a ...
... for their effects on fat development, researchers have discovered ... in mice without some of the side effects attributed ... as harmine, was first isolated more than 150 years ... preparations around the world, the team reports in the ...
Cached Biology News:Genetic roots of bipolar disorder revealed by first genome-wide study of illness 2Genetic roots of bipolar disorder revealed by first genome-wide study of illness 3New Brandeis research sheds light on memory by erasing it 2Fat screen delivers plant-derived chemical with antidiabetic effects 2
(Date:3/4/2015)... BALTIMORE , March 4, 2015 The ... of its 2015 Fellows in the Emerging Leaders in ... fostering future leaders in the field of biosecurity, UPMC ... biosecurity from a wide array of backgrounds, including biological ... private sector. "With the vision and ...
(Date:3/4/2015)... , March 4, 2015 /CNW/ - Resverlogix Corp. ... has completed a collaborative research program with ...  Using Fast Collective Evolution Technology (FACET), Emerald ... all measurements obtained from each of 798 ... 2 clinical trials ASSERT, SUSTAIN and ASSURE. ...
(Date:3/4/2015)... March 4, 2015 Vegalab announced the acquisition ... of last year. As part of the acquisition, Ecowin ... continuing his role as CEO for the company,s ... S.A., will work alongside Koo and oversee developments at ... http://photos.prnewswire.com/prnh/20150303/179218 Koo founded Ecowin in ...
(Date:3/3/2015)... /PRNewswire/ - Aptose Biosciences Inc. (NASDAQ: APTO, TSX: APS), ... that target the underlying mechanisms of cancer, today reported ... December 31, 2014. Effective July 17, 2014, ... 31 to December 31. As a result of that ... the quarter and the seven months ended December 31, ...
Breaking Biology Technology:UPMC Center for Health Security Announces 2015 Emerging Leaders in Biosecurity 2UPMC Center for Health Security Announces 2015 Emerging Leaders in Biosecurity 3Resverlogix Collaborates with Emerald Logic to Identify Factors Driving Drug Response and Efficacy in Phase 2 Program 2Resverlogix Collaborates with Emerald Logic to Identify Factors Driving Drug Response and Efficacy in Phase 2 Program 3Resverlogix Collaborates with Emerald Logic to Identify Factors Driving Drug Response and Efficacy in Phase 2 Program 4Korean Government Program Supports Vegalab's Research and Development 2Korean Government Program Supports Vegalab's Research and Development 3Aptose Biosciences reports results for the quarter and seven months ended December 31, 2014 2Aptose Biosciences reports results for the quarter and seven months ended December 31, 2014 3Aptose Biosciences reports results for the quarter and seven months ended December 31, 2014 4Aptose Biosciences reports results for the quarter and seven months ended December 31, 2014 5Aptose Biosciences reports results for the quarter and seven months ended December 31, 2014 6Aptose Biosciences reports results for the quarter and seven months ended December 31, 2014 7Aptose Biosciences reports results for the quarter and seven months ended December 31, 2014 8Aptose Biosciences reports results for the quarter and seven months ended December 31, 2014 9Aptose Biosciences reports results for the quarter and seven months ended December 31, 2014 10Aptose Biosciences reports results for the quarter and seven months ended December 31, 2014 11Aptose Biosciences reports results for the quarter and seven months ended December 31, 2014 12
... -- Genesis,Pharmaceuticals Enterprises, Inc. (OTC Bulletin Board: ... company with its principal operations,in the People,s ... of its new,corporate website with the domain ... features an overview of the Company, its ...
... (http://www.altogen.com ),announced launch of novel Nanoparticle-based transfection ... animal testing. Transfection is,one of the major laboratory ... cells and tissues. This technique makes it possible ... or a small interfering RNA (siRNA),into the cells ...
... (Nasdaq: NLTX ), announced today that Peter Strumph, ... conferences:, -- Rodman & Renshaw 10th Annual Healthcare ... on Monday, November 10, 2008 at The Palace Hotel ... Annual Healthcare Conference at 9:00 a.m.,ET on Wednesday, November ...
Cached Biology Technology:Genesis Pharmaceuticals Launches New Corporate Website 2Altogen Biosystems Launches New Nanoparticle-based In Vivo Transfection Reagent 2Nile Therapeutics to Present at Two Upcoming Investor Conferences 2
... been designed and created in order to ... genotyping analysis tool. We incorporated the suggestions ... the software. Their main requirements were ease- ... acquisition cost. GeneMarker can perform analysis ...
... The ProLink Express is the first fully ... delivery and transfer operations with complete data ... initial bacterial colony picking through final protein ... is capable of delivering a plate to ...
... phase extraction through columns is a well-known ... applications. Typical applications are in DNA/RNA extraction ... or compound purification in chemical or analytical ... on the Genesis series instruments for smaller ...
... is a multi-functional program that ... from a sequence file for ... sequencing, site-directed mutagenesis, and various ... temperature and secondary structure of ...
Biology Products: