Navigation Links
Ability of brain to protect itself from damage revealed
Date:2/24/2013

The origin of an innate ability the brain has to protect itself from damage that occurs in stroke has been explained for the first time.

The Oxford University researchers hope that harnessing this inbuilt biological mechanism, identified in rats, could help in treating stroke and preventing other neurodegenerative diseases in the future.

'We have shown for the first time that the brain has mechanisms that it can use to protect itself and keep brain cells alive,' says Professor Alastair Buchan, Head of the Medical Sciences Division and Dean of the Medical School at Oxford University, who led the work.

The researchers report their findings in the journal Nature Medicine and were funded by the UK Medical Research Council and National Institute for Health Research.

Stroke is the third most common cause of death in the UK. Every year around 150,000 people in the UK have a stroke.

It occurs when the blood supply to part of the brain is cut off. When this happens, brain cells are deprived of the oxygen and nutrients they need to function properly, and they begin to die.

'Time is brain, and the clock has started immediately after the onset of a stroke. Cells will start to die somewhere from minutes to at most 1 or 2 hours after the stroke,' says Professor Buchan.

This explains why treatment for stroke is so dependent on speed. The faster someone can reach hospital, be scanned and have drugs administered to dissolve any blood clot and get the blood flow re-started, the less damage to brain cells there will be.

It has also motivated a so-far unsuccessful search for 'neuroprotectants': drugs that can buy time and help the brain cells, or neurons, cope with damage and recover afterwards.

The Oxford University research group have now identified the first example of the brain having its own built-in form of neuroprotection, so-called 'endogenous neuroprotection'.

They did this
'/>"/>

Contact: University of Oxford press office
press.office@admin.ox.ac.uk
44-186-528-0530
University of Oxford
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Snooze button on biological clocks improves cell adaptability
2. Stem cell source an important factor, impacting ability to treat myocardial infarction
3. Changes to DNA on-off switches affect cells ability to repair breaks, respond to chemotherapy
4. Enzyme helps cancer cells avoid genetic instability
5. NSF Supports GlobalNSF supports global research to advance science and engineering for sustainability
6. 40 U-M students named Dow Sustainability Fellows
7. Oscillating gel gives synthetic materials the ability to speak
8. Networking ability a family trait in monkeys
9. From the Amazon rainforest to human body cells: Quantifying stability
10. The findings between DNMs and autism provides global view of mutability on human diseases
11. For power and status, dominance and skill trump likability
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/10/2015)... , March 10, 2015  Continuing its 167-year ... Unexpected, Hammacher Schlemmer introduces The Eye Scanning Password ... before granting access to secure websites or sensitive data. ... verify travelers at international borders, the device has a ... pattern points of the iris, converting them into an ...
(Date:3/10/2015)...  NXT-ID, Inc. (NASDAQ: NXTD ... authentication company focused on the growing mobile commerce ... been named the "Number One Best Tech Gift ... Modern ( http://www.rethinkmodern.com/ ) is a web magazine focused ... that have a unique function or design.  ...
(Date:3/3/2015)... , March 3, 2015 ... provider of advanced cryogenic logistics solutions for ... immunotherapies, stem cells, cell lines, clinical research ... medicine, today announced the expansion of its ... Centers, ("Fred Hutch") Clinical Research Division ...
Breaking Biology News(10 mins):Hammacher Schlemmer Introduces The Eye Scanning Password Authenticator 2NXT-ID's Wocket Smart Wallet Named Number One Best Tech Gift for 2015 by Rethink Modern 2NXT-ID's Wocket Smart Wallet Named Number One Best Tech Gift for 2015 by Rethink Modern 3NXT-ID's Wocket Smart Wallet Named Number One Best Tech Gift for 2015 by Rethink Modern 4Cryoport, Inc. Expands Support of Fred Hutchinson Cancer Research Center's Clinical Research Division 2Cryoport, Inc. Expands Support of Fred Hutchinson Cancer Research Center's Clinical Research Division 3
... 18th century natural philosopher Jean-Baptiste Lamarck proposed that the ... cumulative effort, across generations, to reach leaves just out ... abandoned with the advent of modern genetic theories to ... medical illnesses across generations. However, there has long ...
... February 13, 2013, Cleveland: Cleveland Clinic researchers have found ... genetic screening for Lynch syndrome, the most common hereditary, ... online version of the Journal of Clinical Oncology ... cause of colon cancer in adults. The study found ...
... can affect the knowledge and behaviour of their parents, ... London surveyed the families of 160 schoolchildren in the ... about the island,s valuable wetland resources. They found ... the wetland activities were more knowledgeable about wetlands and, ...
Cached Biology News:Life experiences put their stamp on the next generation: New insights from epigenetics 2Cleveland Clinic develops clinical screening program for no.1 genetic cause of colon cancer 2Cleveland Clinic develops clinical screening program for no.1 genetic cause of colon cancer 3Environment schemes for kids influence parents' behavior 2
(Date:3/26/2015)... (PRWEB) March 26, 2015 PRC Clinical, ... announced today several management and executive appointments effective immediately. ... Financial Officer (CFO) and member of the Board of ... Business Operations, and Sue Dowden will assume the position ... and current Chief Operations Officer (COO), has been appointed ...
(Date:3/26/2015)... The Market Element LLC, a leading inbound marketing ... Gig LLC to provide website design, development, and creative ... alliance with Designing Gig represents a pivotal moment for ... end-to-end, digital solution for our clients, which now includes ... president of The Market Element. “For small and mid-sized ...
(Date:3/26/2015)... Massachusetts and CINCINNATI ... Shire plc (LSE: SHP, NASDAQ: SHPG ) ... a three-year, broad research collaboration for rare diseases. The ... develop novel therapies to treat rare diseases with ... commercialization capabilities with Cincinnati Children,s research expertise. As ...
(Date:3/26/2015)... March 26, 2015 PAREXEL International ... clinical research organization , announced today ... agreement to acquire all of the business ... leading provider of specialized pharmacovigilance services, based ... collection, detection, assessment, monitoring, and prevention of ...
Breaking Biology Technology:PRC Clinical Announces Key Management Appointments and Launches East Coast Operations 2PRC Clinical Announces Key Management Appointments and Launches East Coast Operations 3The Market Element LLC and Designing Gig LLC Form Strategic Alliance 2Shire and Cincinnati Children's Establish Rare Disease Research Collaboration 2Shire and Cincinnati Children's Establish Rare Disease Research Collaboration 3Shire and Cincinnati Children's Establish Rare Disease Research Collaboration 4Shire and Cincinnati Children's Establish Rare Disease Research Collaboration 5PAREXEL Announces Execution of Definitive Agreement to Acquire Quantum Solutions India, Strengthening Leadership In Pharmacovigilance Services 2PAREXEL Announces Execution of Definitive Agreement to Acquire Quantum Solutions India, Strengthening Leadership In Pharmacovigilance Services 3PAREXEL Announces Execution of Definitive Agreement to Acquire Quantum Solutions India, Strengthening Leadership In Pharmacovigilance Services 4
... - Oncolytics Biotech Inc.,("Oncolytics") (TSX:ONC, NASDAQ:ONCY) announced today ... Phase 2 clinical trial using intravenous,administration of REOLYSIN(R) ... advanced head and neck cancers. The Principal,Investigator is ... Research Center,(CTRC) at The University of Texas Health ...
... Inc. (Amex:,SGN) announced that it has filed its Form ... of trading of its common stock,on the American Stock ... trade on AMEX will be Friday, September 12, 2008.,Signalife ... for,quotation on both the Over-The-Counter Bulletin Board and the ...
... 8 On Wednesday, October,22, 2008, Wyeth (NYSE: ... quarter. The Company will hold a one-hour conference call ... 22, 2008. Interested,investors and others may listen to the ... webcast, which may be accessed by visiting our website,at ...
Cached Biology Technology:Oncolytics Biotech Inc. Starts Patient Enrolment in U.S. Phase 2 Clinical Trial Investigating REOLYSIN(R) in Combination with Paclitaxel and Carboplatin 2Oncolytics Biotech Inc. Starts Patient Enrolment in U.S. Phase 2 Clinical Trial Investigating REOLYSIN(R) in Combination with Paclitaxel and Carboplatin 3Signalife Announces Anticipated Date of Transition to OTCBB 2
... Beacon Designer designs oligos for SYBR Green, ... NASBA and FRET assays. Highly specific primers ... by automatically interpreting BLAST search results. Primer ... structures identified by connecting to the Mfold ...
Human IL-17D Affinity Purified Polyclonal Ab...
... Consists of the LVF-UV-HL, LVF-CUV-ADP, FHS-LVF and ... and low-pass Linear Variable Filters to create ... adjustable center wavelength and adjustable bandpass. Each ... and blocking band (99.8%). These filters ...
Agar, 500 g. Noble Agar.Moisture: < 10%, ash: < 1.6%, EEO (-mr): < 0.450 (pH 8.4). Category: Nucleotides & Enzymes & Biochemicals, Ultrapure Biochemicals ....
Biology Products: