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A transcription factor called SLUG helps determines type of breast cancer
Date:5/2/2014

, suggesting that SLUG may affect stem-cell activity necessary for tumor formation.

Discussion: First author Sarah Phillips, a Ph.D. student in genetics at the Sackler School of Graduate Biomedical Sciences at Tufts University:

"The study gives us insight into a potential source of cellular imbalance in breast tissues that can become cancerous. It also builds on the relationship between the levels of SLUG and the levels of cells that are associated with aggressive cancers. Breast cancer is very complex biologically, but any information we can find that could reduce this cellular over-growth could eventually be another tool to treat breast cancer at its sources."


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Contact: Siobhan Gallagher
siobhan.gallagher@tufts.edu
617-636-6586
Tufts University, Health Sciences Campus
Source:Eurekalert

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