Navigation Links
A surprising new function for small RNAs in evolution
Date:4/19/2013

It has long been known that certain proteins, known as transcription factors, directly control the way in which information is read from DNA. As a result, it is widely believed that changes in genes encoding such proteins underlie the mechanisms responsible for evolutionary adaptation. The idea that small RNA molecules, so-called microRNAs, may play an important part in evolutionary changes to animals' appearance is completely new. An international team of researchers, including Christian Schltterer and Alistair McGregor from the Institute of Population Genetics of the University of Veterinary Medicine, Vienna (Vetmeduni Vienna), has now published a study that describes such an evolutionary mechanism.

Small and large bald patches

Insect bodies are generally covered with a large number of microscopic hairs. This is the case for the legs of many closely related species of the fruit fly genus Drosophila, although the animals have a bald patch on the second pair of legs, intriguingly known as the naked valley. Previous work had shown that the size of this patch is regulated by the gene ultrabithorax (Ubx) and that it differs between species. However, the work at the Vetmeduni Vienna showed that similar differences are shown by individuals from different populations of Drosophila melanogaster.

Their search for the genetic basis of the variation led the researchers to a segment of fruit fly DNA that contained four genes. Three of these genes were known to encode proteins with no role in the development of the hairs. The fourth gene, known as miR-92a, encodes a microRNA. Previous experiments had shown that an increase in activity of the miR-92a gene was associated with a loss of hairs from the animals' wings. By overexpressing the gene in the legs of the fruit flies, the scientists were able to cause hair loss on the animals' legs.

Schltterer is naturally excited by the findings. "This is the first ex
'/>"/>

Contact: Christian Schlötterer
christian.schloetterer@vetmeduni.ac.at
43-125-077-4300
University of Veterinary Medicine -- Vienna
Source:Eurekalert

Page: 1 2

Related biology news :

1. Surprising findings on hydrogen production in green algae
2. Scientists find surprising new influence on cancer genes
3. Computer modeling reveals how surprisingly potent hepatitis C drug works
4. New look at cell membrane reveals surprising organization
5. Climate changes effects on temperate rain forests surprisingly complex
6. Surprising teaching tool in K-12 science education -- Zebrafish research
7. Despite their thick skins, alligators and crocodiles are surprisingly touchy
8. Surprising demographic shifts in endangered monkey population challenge conservation expectations
9. Nuclear weapons surprising contribution to climate science
10. Seabirds study shows plastic pollution reaching surprising levels off coast of Pacific Northwest
11. First-of-its-kind study reveals surprising ecological effects of earthquake and tsunami
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/7/2014)... -- Leading Biometric companies aim to provide consumers ... transactions.  Companies in focus today are: NXT-ID, Inc. (NASDAQ: ... ), Google Inc. (NASDAQ: GOOG ), Microsoft Corporation ... EBAY ) and MasterCard Inc. (NYSE: MA) NXT-ID, ... authentication company focused on the growing mobile commerce is pleased ...
(Date:11/6/2014)... cancer deaths occur because of metastasis, yet progress ... been slow. , "It,s been particularly challenging to ... Gujral, research fellow in systems biology at Harvard ... detected until after they,ve already metastasized." , Gujral ... that should help researchers better understand how metastasis ...
(Date:11/6/2014)... Medicine, Inc, a Baltimore-based bioinformatics company focused on ... a research collaboration with the international leader in ... CSBR). , "There are many companies utilizing advances ... TumorGraft technology is unique in a way that ... vast amounts of valuable data. Our bioinformatic analysis ...
Breaking Biology News(10 mins):Universal Authentication Methods Provide More Secure Operations for Biometrics Devices - Company Joins FIDO Alliance for Consumer Protection 2Universal Authentication Methods Provide More Secure Operations for Biometrics Devices - Company Joins FIDO Alliance for Consumer Protection 3Universal Authentication Methods Provide More Secure Operations for Biometrics Devices - Company Joins FIDO Alliance for Consumer Protection 4Universal Authentication Methods Provide More Secure Operations for Biometrics Devices - Company Joins FIDO Alliance for Consumer Protection 5Universal Authentication Methods Provide More Secure Operations for Biometrics Devices - Company Joins FIDO Alliance for Consumer Protection 6Migration negation 2Migration negation 3Insilico Medicine, Inc announces research collaboration with Champions Oncology, Inc 2
... with backache caused by nerve root pain ?commonly known ... if therapeutic ultrasound can help their condition. , Dr ... for Rehabilitation Science need 30 volunteers aged 22-55 who ... not pregnant and have not had previous spinal surgery. ...
... in high tech tools, researchers have identified three proteins ... to 20 months before the rejection occurred. , Lung ... recipients, about 45% over five years, said lead investigator ... way to predict which transplants will fail, and when ...
... the survival of many types of cells stimulates rapid ... connect the cerebral cortex with the spinal cord and ... sclerosis (ALS or Lou Gehrig's disease). In the ... Massachusetts General Hospital (MGH) and the Harvard Stem Cell ...
Cached Biology News:Proteins may predict lung transplant rejection 2Proteins may predict lung transplant rejection 3Growth factor stimulates rapid extension of key motor neurons in brain 2
(Date:11/26/2014)... Theravalues Corporation est fier d,annoncer le ... au salon Hi Europe 2014 (du 2 au ... Curcumine la plus biodisponible actuellement sur le ... des ingrédients approuvés par les règlements européens. ... dans la racine de curcuma ( Curcuma longa ...
(Date:11/26/2014)... , 25 novembre 2014 /PRNewswrie/ -- Theravalues Corporation ... il mercato europeo in occasione di Hi Europe 2014 ... ). Si tratta della curcumina con la ... amorfa (senza cristalli) e ingredienti approvati dalle norme europee. ... nella spezia della pianta curcumina ( Curcuma longa ) ...
(Date:11/24/2014)... 24, 2014  IGI Laboratories, Inc. (NYSE MKT: IG), ... generic pharmaceutical company, today announced it has submitted an ... Food and Drug Administration (FDA), which brings the Company,s ... with eighteen submissions now pending at the FDA. ... of the Company, commented, "Our team here at IGI ...
(Date:11/24/2014)... Nov. 24, 2014  Last week, Representatives ... (D-NC) took a bold bipartisan step on ... the OPEN Act. Original co-sponsors of the legislation ... Act will incentivize drug makers and innovators to ... and pediatric cancers, which opens the door to ...
Breaking Biology Technology:La curcumine présentant la plus haute biodisponibilité bientôt en vente en Europe 2La curcumine présentant la plus haute biodisponibilité bientôt en vente en Europe 3La curcumina con la maggiore biodisponibilità di sempre farà il suo debutto in Europa 2La curcumina con la maggiore biodisponibilità di sempre farà il suo debutto in Europa 3IGI Laboratories, Inc. Announces ANDA Submission 2OPEN Act Introduced to Repurpose Drugs for Rare Diseases 2
... Duke University bioengineers have not only figured out a ... cells, they can now slip them into the command center ... report back important information or drop off payloads. Using ... that has an uncanny ability to penetrate human cells, ...
... 28 /PRNewswire-FirstCall/ - Neuro-Biotech Corporation (PINKSHEETS: MRES) (OTCQB: MRES) ... 1 SymPath(R) TO EVALUATE THE ... (DBH), THAT IS RELEASED WITH NORADRENALINE WITHIN THE BLOOD ... NEURO # 2 AXIS(TM) ...
... Sept. 28 /PRNewswire-Asia-FirstCall/ -- ... ... ... first_result; // Results are keyed by longUrl, so we need to grab the first one. for ...
Cached Biology Technology:Sneaking spies into a cell's nucleus 2Sneaking spies into a cell's nucleus 3NEURO-BIOTECH DISCLOSES ITS LIST OF LICENSES 2Tongjitang Chinese Medicines Company Enters into Share Transfer Agreement 2Tongjitang Chinese Medicines Company Enters into Share Transfer Agreement 3Tongjitang Chinese Medicines Company Enters into Share Transfer Agreement 4Tongjitang Chinese Medicines Company Enters into Share Transfer Agreement 5Tongjitang Chinese Medicines Company Enters into Share Transfer Agreement 6Tongjitang Chinese Medicines Company Enters into Share Transfer Agreement 7Tongjitang Chinese Medicines Company Enters into Share Transfer Agreement 8