Navigation Links
A surprising new function for small RNAs in evolution
Date:4/19/2013

It has long been known that certain proteins, known as transcription factors, directly control the way in which information is read from DNA. As a result, it is widely believed that changes in genes encoding such proteins underlie the mechanisms responsible for evolutionary adaptation. The idea that small RNA molecules, so-called microRNAs, may play an important part in evolutionary changes to animals' appearance is completely new. An international team of researchers, including Christian Schltterer and Alistair McGregor from the Institute of Population Genetics of the University of Veterinary Medicine, Vienna (Vetmeduni Vienna), has now published a study that describes such an evolutionary mechanism.

Small and large bald patches

Insect bodies are generally covered with a large number of microscopic hairs. This is the case for the legs of many closely related species of the fruit fly genus Drosophila, although the animals have a bald patch on the second pair of legs, intriguingly known as the naked valley. Previous work had shown that the size of this patch is regulated by the gene ultrabithorax (Ubx) and that it differs between species. However, the work at the Vetmeduni Vienna showed that similar differences are shown by individuals from different populations of Drosophila melanogaster.

Their search for the genetic basis of the variation led the researchers to a segment of fruit fly DNA that contained four genes. Three of these genes were known to encode proteins with no role in the development of the hairs. The fourth gene, known as miR-92a, encodes a microRNA. Previous experiments had shown that an increase in activity of the miR-92a gene was associated with a loss of hairs from the animals' wings. By overexpressing the gene in the legs of the fruit flies, the scientists were able to cause hair loss on the animals' legs.

Schltterer is naturally excited by the findings. "This is the first ex
'/>"/>

Contact: Christian Schlötterer
christian.schloetterer@vetmeduni.ac.at
43-125-077-4300
University of Veterinary Medicine -- Vienna
Source:Eurekalert

Page: 1 2

Related biology news :

1. Surprising findings on hydrogen production in green algae
2. Scientists find surprising new influence on cancer genes
3. Computer modeling reveals how surprisingly potent hepatitis C drug works
4. New look at cell membrane reveals surprising organization
5. Climate changes effects on temperate rain forests surprisingly complex
6. Surprising teaching tool in K-12 science education -- Zebrafish research
7. Despite their thick skins, alligators and crocodiles are surprisingly touchy
8. Surprising demographic shifts in endangered monkey population challenge conservation expectations
9. Nuclear weapons surprising contribution to climate science
10. Seabirds study shows plastic pollution reaching surprising levels off coast of Pacific Northwest
11. First-of-its-kind study reveals surprising ecological effects of earthquake and tsunami
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/22/2014)... Gables, Fla. (April 21, 2014) -- There are all ... their feathers and spread their colorful tails; satin bowbirds ... with blue and shiny objects; and European bitterling males ... species has evolved a unique method to communicate with ... "Signaling can have profound fitness implications ...
(Date:4/22/2014)... 2014 Scientists from the Florida campus of The ... that plays a critical but previously unknown role in ... showed a novel role for a protein known as ... eLife , a publisher supported by the Howard ... Wellcome Trust. , "This is a critical building block ...
(Date:4/22/2014)... International Science Consortium Ltd.,s nanotechnology expert will present a ... hazard assessment" at the 7th International Nanotoxicology Congress ... Turkey. , Dr. Monita Sharma will outline a ... National Academy of Sciences, " Toxicity Testing in the ... recommends use of non-animal methods involving human cells and ...
Breaking Biology News(10 mins):Best practices in communication for the animal world 2Best practices in communication for the animal world 3Scientists identify critical new protein complex involved in learning and memory 2
... air quality apparently affects the running times of women in ... environmental engineer Linsey Marr. Marr,s findings come from a ... air pollutant concentrations in seven marathons over a period of ... finishing times were compared with the course record and contrasted ...
... for Microbiology (ASM) Roche Diagnostics Alice C. Evans Award ... Science Director, Walter Reed Army Institute of Research, ... scientists. This award recognizes contributions toward the full participation ... in honor of Alice C. Evans, the first woman ...
... monkeys, mothers who weigh more and have had previous ... babies than mothers who weigh less and are less ... of California, Davis are using this natural variation in ... mother,s milk sends a reliable signal to infants about ...
Cached Biology News:Women more affected than men by air pollution when running marathons 2Baby monkeys receive signals through their mother's breast milk 2
(Date:1/15/2014)... 2014  Bill Jacobs Automotive, a group of car dealerships headquartered ... the Heartland Blood Center and offering free oil change coupons ... place Saturday, Jan. 18 at the Bill Jacobs Cadillac and ... (Photo: http://photos.prnewswire.com/prnh/20140115/MN46637 )  The Bill Jacobs ...
(Date:1/15/2014)... Westlake Village, Calif. (PRWEB) January 15, 2014 ... cancer treatment and management through the genomic analysis of ... will offer Therapy Finder™, a web-based cancer decision support ... a reporting option with Cynvenio’s ClearID™ genomic test, Therapy ...
(Date:1/15/2014)... A study has been launched to test whether technology ... help to tackle the problem of obesity.  This unique healthcare ... based in Stowmarket) and academics at University Campus Suffolk is ... which is inspired by equipment used to collect data about ...
(Date:1/15/2014)... (PRWEB) January 15, 2014 DTS Language ... its Online Web Portal for Life Science organizations who need ... specify the subject matter of their documents in advance with ... help reduce time-to-delivery of translations, often a critical factor in ...
Breaking Biology Technology:Join the Bill Jacobs Auto blood drive and receive a free oil change 2Cynvenio Offers New Breast Cancer Therapy Finder Application for its ClearID Breast Cancer Genomic Test 2Cynvenio Offers New Breast Cancer Therapy Finder Application for its ClearID Breast Cancer Genomic Test 3Formula 1 Technology Tackles Obesity in Unique Healthcare Partnership 2Formula 1 Technology Tackles Obesity in Unique Healthcare Partnership 3Formula 1 Technology Tackles Obesity in Unique Healthcare Partnership 4DTS Improves Efficiency for Life Science Document Translations 2
... Reliable, PCR-based mycoplasma detection , Douglas ... , Stratagene introduces the Mycoplasma PCR Primer Set ... method which specifically amplifies an 874-bp,PCR product from ... contains an internal,control template that serves as a ...
... kit for site-directed mutagenesis of,large plasmids ... Holly Hogrefe ,Jeff Braman ,Stratagene , The ... exceeding 80%. We have created a new ... QuikChange XL,site-directed mutagenesis kit ...
... transduction research and drug screening , , ... Inc. , , Stratagene has successfully expressed and ... constitutively active mutant (MEK1 CA ),using the ESP ... MEKs, produced in yeast, are full length and ...
Cached Biology Technology:A New PCR-based Mycoplasma Detection Method 2A New PCR-based Mycoplasma Detection Method 3A New PCR-based Mycoplasma Detection Method 4A New PCR-based Mycoplasma Detection Method 5A New PCR-based Mycoplasma Detection Method 6High-Efficiency Site-Directed Mutagenesis of Large Plasmid Vectors 2High-Efficiency Site-Directed Mutagenesis of Large Plasmid Vectors 3High-Efficiency Site-Directed Mutagenesis of Large Plasmid Vectors 4Production of Full-Length, Biologically Active MEK1WT and MEK1CA 2Production of Full-Length, Biologically Active MEK1WT and MEK1CA 3Production of Full-Length, Biologically Active MEK1WT and MEK1CA 4Production of Full-Length, Biologically Active MEK1WT and MEK1CA 5
... Blocker Array II can be used ... against various proteins and sera that are ... carriers. The array contains spots for 19 ... Application: Determination of antibody crossreactivity and species ...
... Tecans new HydroFlex platform provides excellent ... range of 96-well format applications, including ... protein arrays, and vacuum filtration-to-waste, such ... outstanding on-line control features set new ...
... and Accurate Results Laser Capture Microdissection ... sensitivity and accuracy of molecular assays by ... and multi-cellular structures isolated from whole tissue ... microdissection-developed in 1996 at the National Institutes ...
...
Biology Products: