Navigation Links
A surprising new function for small RNAs in evolution
Date:4/19/2013

It has long been known that certain proteins, known as transcription factors, directly control the way in which information is read from DNA. As a result, it is widely believed that changes in genes encoding such proteins underlie the mechanisms responsible for evolutionary adaptation. The idea that small RNA molecules, so-called microRNAs, may play an important part in evolutionary changes to animals' appearance is completely new. An international team of researchers, including Christian Schltterer and Alistair McGregor from the Institute of Population Genetics of the University of Veterinary Medicine, Vienna (Vetmeduni Vienna), has now published a study that describes such an evolutionary mechanism.

Small and large bald patches

Insect bodies are generally covered with a large number of microscopic hairs. This is the case for the legs of many closely related species of the fruit fly genus Drosophila, although the animals have a bald patch on the second pair of legs, intriguingly known as the naked valley. Previous work had shown that the size of this patch is regulated by the gene ultrabithorax (Ubx) and that it differs between species. However, the work at the Vetmeduni Vienna showed that similar differences are shown by individuals from different populations of Drosophila melanogaster.

Their search for the genetic basis of the variation led the researchers to a segment of fruit fly DNA that contained four genes. Three of these genes were known to encode proteins with no role in the development of the hairs. The fourth gene, known as miR-92a, encodes a microRNA. Previous experiments had shown that an increase in activity of the miR-92a gene was associated with a loss of hairs from the animals' wings. By overexpressing the gene in the legs of the fruit flies, the scientists were able to cause hair loss on the animals' legs.

Schltterer is naturally excited by the findings. "This is the first ex
'/>"/>

Contact: Christian Schlötterer
christian.schloetterer@vetmeduni.ac.at
43-125-077-4300
University of Veterinary Medicine -- Vienna
Source:Eurekalert

Page: 1 2

Related biology news :

1. Surprising findings on hydrogen production in green algae
2. Scientists find surprising new influence on cancer genes
3. Computer modeling reveals how surprisingly potent hepatitis C drug works
4. New look at cell membrane reveals surprising organization
5. Climate changes effects on temperate rain forests surprisingly complex
6. Surprising teaching tool in K-12 science education -- Zebrafish research
7. Despite their thick skins, alligators and crocodiles are surprisingly touchy
8. Surprising demographic shifts in endangered monkey population challenge conservation expectations
9. Nuclear weapons surprising contribution to climate science
10. Seabirds study shows plastic pollution reaching surprising levels off coast of Pacific Northwest
11. First-of-its-kind study reveals surprising ecological effects of earthquake and tsunami
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/23/2014)... potential for clinical use of induced pluripotent stem ... previously been hindered by the risk of dysregulated ... ability to use etoposide treatment to halt teratoma ... disease, specifically acute myocardial infarction, is demonstrated in ... , a peer-reviewed journal from Mary Ann Liebert, ...
(Date:7/23/2014)... do mollusks, starfish, and corals have in common? ... all calcifiersorganisms that use calcium from their environment ... stability and protection. , The July issue of ... Marine Biological Laboratory, addresses the challenges faced by ... As atmospheric carbon dioxide rises, the world,s oceans ...
(Date:7/23/2014)... Massachusetts , July 23, 2014 ... in its new report, GLOBAL MARKETS AND TECHNOLOGIES ... related technologies is expected to grow to nearly $154.4 ... rate (CAGR) of 10.1%. The image, flow, and level ...      (Logo: http://photos.prnewswire.com/prnh/20140723/694805 ) , ...
Breaking Biology News(10 mins):Calcification in changing oceans explored in special issue of The Biological Bulletin 2Global Market for Sensors to Reach Nearly $154.4 Billion in 2020; Image Sensors Moving at 11.7% 2Global Market for Sensors to Reach Nearly $154.4 Billion in 2020; Image Sensors Moving at 11.7% 3
... fractures occur in the United States as a result of ... to rapid bone fusion but with limited mechanical strength often ... difficult to harvest without pain and severe morbidity. Funded by ... the Department of Chemistry, Chemical Biology and Biomedical Engineering at ...
... Washington two years ago launched an ambitious project harnessing the ... Foldit, turns one of the hardest problems in molecular biology ... people have now played a game that asks them to ... a princess. Results published Thursday (Aug. 5) in the ...
... shallow, nearshore waters, researchers from Stony Brook University ... first multi-year survey of the population of Antarctic ... near Livingston Island and discovered that nearshore waters ... waters. They also found that the nearshore waters ...
Cached Biology News:NSF funds innovative approach to biomimetic nanofiber bone regeneration 2NSF funds innovative approach to biomimetic nanofiber bone regeneration 3Gaming for a cure: Computer gamers tackle protein folding 2Gaming for a cure: Computer gamers tackle protein folding 3Gaming for a cure: Computer gamers tackle protein folding 4First nearshore survey of Antarctic krill reveals high density, stable population in shallow waters 2
(Date:7/23/2014)... (MIPT and Russian Quantum Center at Skolkovo) and ... and the Institute of Physics in Bratislava, Slovakia) ... of particles passing through an amplifier and, conversely, ... are provided in an article published in the ... , Quantum entangled particles are considered to be ...
(Date:7/23/2014)... (PRWEB) July 23, 2014 Last year, ... Systems , a leading global provider of data management ... with TrialMaster, a leading-edge system for electronic data capture ... of universal design and study execution tools added TrialMaster ... and much anticipated version of Transform for TrialMaster, is ...
(Date:7/23/2014)... DuPont Pioneer announced today that Neal Gutterson, ... Agricultural Biotechnology (ABT), effective July 21, 2014. Gutterson joins ... as president, chief executive officer and board member. , ... seed and crop protection industry to this integral role ... president of DuPont Pioneer. “I am looking forward to ...
(Date:7/23/2014)... 2014  Sofinnova Ventures, a Menlo Park ... of Sofinnova Venture Partners IX, L.P. at the hard ... initial fund target of $425 million. Sofinnova ... Consistent with recent funds, SVP IX will provide capital ... along with select investments in earlier stage opportunities. Investments ...
Breaking Biology Technology:Scientists find way to maintain quantum entanglement in amplified signals 2Scientists find way to maintain quantum entanglement in amplified signals 3Scientists find way to maintain quantum entanglement in amplified signals 4Formedix and OmniComm Systems® Partnership Strengthened with the Release of Enhanced TrialMaster® Integration for EDC Build 2Formedix and OmniComm Systems® Partnership Strengthened with the Release of Enhanced TrialMaster® Integration for EDC Build 3DuPont Pioneer Names Neal Gutterson to Lead Agricultural Biotechnology 2DuPont Pioneer Names Neal Gutterson to Lead Agricultural Biotechnology 3Sofinnova Raises $500 Million Biotech Venture Fund 2
... Hard-to-transfect Cells , Dmitriy ... Kelnar, David Brown, Ambion, Inc. , ... RNA interference (RNAi) is a powerful , ... genes. It is used routinely for gene function analysis, target , ...
... Trace amounts of ribonuclease (RNase) , ... ubiquitous in the laboratory environment--on your skin, in the , ... , open to the air--it ... or eliminate RNase contamination. However, determining which , ...
... , High Quality Custom Synthesis ... Mouse, and Rat , Genomes , ... Silencer siRNA Libraries , , ... Quality Custom RNA Synthesis by Ambion Finding a highly effective ...
Cached Biology Technology:Delivering siRNAs to Difficult Cell Types 2Delivering siRNAs to Difficult Cell Types 3Delivering siRNAs to Difficult Cell Types 4Delivering siRNAs to Difficult Cell Types 5Delivering siRNAs to Difficult Cell Types 6Delivering siRNAs to Difficult Cell Types 7Combat RNase Contamination in the Lab 2Combat RNase Contamination in the Lab 3Combat RNase Contamination in the Lab 4Combat RNase Contamination in the Lab 5IMPROVE SILENCING SUCCESS: siRNAs THAT WORK BETTER! 2IMPROVE SILENCING SUCCESS: siRNAs THAT WORK BETTER! 3IMPROVE SILENCING SUCCESS: siRNAs THAT WORK BETTER! 4IMPROVE SILENCING SUCCESS: siRNAs THAT WORK BETTER! 5IMPROVE SILENCING SUCCESS: siRNAs THAT WORK BETTER! 6IMPROVE SILENCING SUCCESS: siRNAs THAT WORK BETTER! 7IMPROVE SILENCING SUCCESS: siRNAs THAT WORK BETTER! 8IMPROVE SILENCING SUCCESS: siRNAs THAT WORK BETTER! 9IMPROVE SILENCING SUCCESS: siRNAs THAT WORK BETTER! 10
Request Info...
FITC~Bovine Serum Albumin...
... the premium quality siRNAs you need for ... be readily ordered online by providing either ... providing the sense and antisense siRNA sequences. ... Silencer Pre-designed siRNAs, which are already designed ...
, Premium quality synthesis and purification , You provide the sequence, we'll do the rest , Rigorous quality control , Your choice of purification method, amount and format , Available annealed...
Biology Products: