Navigation Links
A new type of nerve cell found in the brain
Date:12/21/2012

Scientists at Karolinska Institutet in Sweden, in collaboration with colleagues in Germany and the Netherlands, have identified a previously unknown group of nerve cells in the brain. The nerve cells regulate cardiovascular functions such as heart rhythm and blood pressure. It is hoped that the discovery, which is published in the Journal of Clinical Investigation, will be significant in the long term in the treatment of cardiovascular diseases in humans.

The scientists have managed to identify in mice a previously totally unknown group of nerve cells in the brain. These nerve cells, also known as 'neurons', develop in the brain with the aid of thyroid hormone, which is produced in the thyroid gland. Patients in whom the function of the thyroid gland is disturbed and who therefore produce too much or too little thyroid hormone, thus risk developing problems with these nerve cells. This in turn has an effect on the function of the heart, leading to cardiovascular disease.

It is well-known that patients with untreated hyperthyroidism (too high a production of thyroid hormone) or hypothyroidism (too low a production of thyroid hormone) often develop heart problems. It has previously been believed that this was solely a result of the hormone affecting the heart directly. The new study, however, shows that thyroid hormone also affects the heart indirectly, through the newly discovered neurons.

"This discovery opens the possibility of a completely new way of combating cardiovascular disease", says Jens Mittag, group leader at the Department of Cell and Molecular Biology at Karolinska Institutet. "If we learn how to control these neurons, we will be able to treat certain cardiovascular problems like hypertension through the brain. This is, however, still far in the future. A more immediate conclusion is that it is of utmost importance to identify and treat pregnant women with hypothyroidism, since their low level of thyroid hormone
'/>"/>

Contact: Press Office
pressinfo@ki.se
46-852-486-077
Karolinska Institutet
Source:Eurekalert

Page: 1 2

Related biology news :

1. Removing protein garbage in nerve cells may help control 2 neurodegenerative diseases
2. Protein creates paths for growing nerve cells
3. Hybrid tunnel may help guide severed nerves back to health
4. Carbon nanotubes lower nerve-damaging chloride in cells
5. OHSU study shows that a molecule critical to nerve cells increases drammatically during hypertension
6. NIH-funded researchers show possible trigger for MS nerve damage
7. A step forward in regenerating and repairing damaged nerve cells
8. Stem cells + nanofibers = Promising nerve research
9. MRI research sheds new light on nerve fibers in the brain
10. MRI research sheds new light on nerve fibres in the brain
11. MBL scientists discover nerves control iridescence in squid’s remarkable electric skin
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/20/2015)... DUBLIN , May 20, 2015 ... Markets ( http://www.researchandmarkets.com/research/h8t4x6/5year ) has announced the ... of the Global Iris Recognition Market" ... http://photos.prnewswire.com/prnh/20130307/600769) , ,This research service analyses ... across the government and commercial sectors, ...
(Date:5/19/2015)... DUBLIN , May 19, 2015 /PRNewswire/ ... ) has announced the addition of the  ... their offering.  ,     (Logo: http://photos.prnewswire.com/prnh/20130307/600769) , ,A ... provides an in-depth analysis of the current ... introduction of gene-based tests, their working principles ...
(Date:5/11/2015)... JOSE, Calif. , May 11, 2015 /PRNewswire/ ... developer of human interface solutions, today announced the ... Vice President and Chief Financial Officer, reporting to ... Ali replaces Synaptics, current Chief Financial Officer, ... December 2014. Mr. Ali brings ...
Breaking Biology News(10 mins):Global Iris Recognition Market Report 2015 - 5-Year Opportunity Analysis 2Global Genetic Testing Market Outlook 2018 2Synaptics Appoints Wajid Ali as Senior Vice President and Chief Financial Officer 2
... molecular fingerprints of what your cells are up to and ... cancer. You,ve likely heard about metabolites; your physician probably ... at your annual physical. Scientists suspect we have about 3,000 ... different compounds in our bodies. Dr. Sreekumar, ...
... 2009 A review by researchers at Northwestern University ... of the utility of probiotics in the treatment of ... 35624 was the only probiotic strain out of ... improve symptoms of IBS, including abdominal pain, bloating and ...
... at your desk and suddenly your heart is beating ... on fumes. It is a shocking, uncomfortable and frightening ... cause of sudden cardiac death or SCD, a condition ... States. Scientists are now closer to understanding what causes ...
Cached Biology News:Molecular fingerprints point the way to earlier cancer diagnosis and more targeted treatment 2Molecular fingerprints point the way to earlier cancer diagnosis and more targeted treatment 3Molecular fingerprints point the way to earlier cancer diagnosis and more targeted treatment 4Review of probiotic trial research finds only Bifantis able to claim efficacy for IBS symptoms 2Ten genes identified in connection with sudden cardiac death 2
(Date:5/29/2015)... IRVING, Texas , May 29, 2015 /PRNewswire/ ... company focused on fulfilling the promise of precision ... five studies that demonstrate the clinical utility of ... comprehensive tumor profiling service, in helping to identify ... aggressive tumors. In each of the studies, results ...
(Date:5/29/2015)... May 29, 2015 Translation is frequently listed ... for a good reason--if used in a way that is ... offering of a business product or service offering. , ... have a positive effect on a company's bottom line: , ... anyone in the world can use, why not offer it ...
(Date:5/28/2015)... , May 27, 2015 Research ... addition of Jain PharmaBiotech,s new report ... their offering. An increasing use ... industries is anticipated. Nanotechnology will be applied ... from formulations for optimal delivery to diagnostic ...
(Date:5/28/2015)... LAWRENCEVILLE, N.J. , May 28, 2015 ... announced that it has received commitments from two institutional ... million of the Company,s common stock in an at-the-market ... warrants to purchase common stock. The Company ... pursuant to which the Company agreed to sell an ...
Breaking Biology Technology:Multi-Platform Tumor Profiling from Caris Life Sciences Identifies Targeted Treatment Options for Patients with Rare and/or Aggressive Tumors 2Multi-Platform Tumor Profiling from Caris Life Sciences Identifies Targeted Treatment Options for Patients with Rare and/or Aggressive Tumors 3Multi-Platform Tumor Profiling from Caris Life Sciences Identifies Targeted Treatment Options for Patients with Rare and/or Aggressive Tumors 4Multi-Platform Tumor Profiling from Caris Life Sciences Identifies Targeted Treatment Options for Patients with Rare and/or Aggressive Tumors 5Multi-Platform Tumor Profiling from Caris Life Sciences Identifies Targeted Treatment Options for Patients with Rare and/or Aggressive Tumors 6Three Ways Translation Can Help Businesses Grow 2Global Nanobiotechnology Market 2015-2024 - Applications, Markets and Companies 2Global Nanobiotechnology Market 2015-2024 - Applications, Markets and Companies 3Celsion Corporation Announces $8 Million At-The-Market Registered Direct Offering 2Celsion Corporation Announces $8 Million At-The-Market Registered Direct Offering 3
... In my last column, I reviewed some of the key ... experiences of 25 of the largest practitioners of outsourcing in ... another study conducted by the consulting firm DiamondCluster of over ... report can be downloaded here . ...
... Interest in UW-Madison's RFID Lab is so strong that ... after all of the 120 spots available for the tour were ... is canceling" to make room for those on the list, said ... "It shows that people are really excited about RFID." , ,Visitors ...
... eagerly await responses from the FDA to requests ... submissions for premarket clearance of medical devices, and ... of FDA letter -- a warning letter -- ... written notice that the FDA has identified significant ...
Cached Biology Technology:Is outsourcing reaching its limits or simply pausing for breath? - Part II 2Is outsourcing reaching its limits or simply pausing for breath? - Part II 3Is outsourcing reaching its limits or simply pausing for breath? - Part II 4It's in the mail -- Responding to an FDA warning letter 2It's in the mail -- Responding to an FDA warning letter 3It's in the mail -- Responding to an FDA warning letter 4
... System is intended for use in the ... an in-house validated in vitro nucleic acid ... • The CHEMICON ... capture assay designed to detect amplified nucleic ...
... these culture chambers produce cell yields in ... range and are useful alternatives to multiple ... mechanical • strength and structural integrity • ... Certified nonpyrogenic and sterilized by gamma irradiation, ...
BD BioCoat Collagen IV 150 mm Culture Dishes...
Gridded Cell Culture Petri Dish (20 mm molded in base), tissue-culture treated...
Biology Products: