Navigation Links
A new computational method for timing the tree of life
Date:11/6/2012

With its deeply embedded roots, sturdy trunk and dense profusion of branches, the Tree of Life is a structure of nearly unfathomable complexity and beauty. While major strides have been made to establish the evolutionary hierarchy encompassing every living species, the project is still in its infancy.

At Arizona State University's Biodesign Institute, Sudhir Kumar has been filling in the Tree of Life by developing sophisticated methods and bioinformatics tools. His latest research, which appeared on the advance online edition of the Proceedings of the National Academy of Sciences will uniquely enable scientists to analyze very large datasests to set time to the multitude of branching points (nodes) on the tree, each representing a point of species divergence from a common ancestor. The new method differs significantly from currently used techniques and excels in providing results of equal or greater accuracy at speeds of 1000 times or faster.

For the proper study of evolutionary history, two components are key: the relationships between organisms (known as phylogeny) and their times of divergence. As Kumar explains, the powerful technique for estimating the time of divergence between species was initially realized over four decades ago, when the concept of molecular clocks was introduced. Initially the idea rested on the assumption that alterations in either the amino acid sequences of proteins or the nucleotide sequences of DNA between various species accumulate at a uniform rate over time and can be used to evaluate divergence times. The resulting phylogenetic structure is known as a "TimeTree," that is, a tree of life scaled to time.

Prior to the use of molecular clocks, morphological changes between species were the primary means of identifying divergence times. Since then, molecular clocks have proved a vital tool for evolutionary biologists, supplementing the fossil record and providing a powerful means to time t
'/>"/>

Contact: Richard Harth
richard.harth@asu.edu
Arizona State University
Source:Eurekalert  

Page: 1 2 3

Related biology news :

1. GW announces creation of Computational Biology Institute to conduct integrated research
2. George Washington University Computational Biology Director solves 200-year-old oceanic mystery
3. New 3-D stem cell culture method published in JoVE
4. New methods for better purification of wastewater
5. More effective method of imaging proteins
6. New method for estimating parameters may boost biological models
7. New paper by Notre Dame researchers describes method for cleaning up nuclear waste
8. Scientists discover new method of proton transfer
9. Oceanographers develop method for measuring the pace of life in deep sediments
10. Notre Dame researchers using novel method to combat malaria drug resistance
11. Rapid method of assembling new gene-editing tool could revolutionize genetic research
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
A new computational method for timing the tree of life
(Date:8/31/2014)... One of the greatest challenges in modern medicine is ... but with minimal toxicity and side-effects to the patient. ... of the drug molecule. Ideally, the drug should have ... target, so that it binds it with high specificity. ... developed a synthetic amino acid that can impact the ...
(Date:8/31/2014)... Climate Change , suggests that if current trends continue ... global targets for total greenhouse gas (GHG) emissions in 2050. ... carefully about the food we choose and its environmental impact. ... one of a number of actions that need to be ... enough food for all. , As populations rise and ...
(Date:8/29/2014)... Researchers at UC Davis have made some surprising ... infection. Studying simian immunodeficiency virus (SIV), the team ... Paneth cells are early responders to viral invasion ... producing a cytokine called interleukin-1 beta (IL-1β). ... IL-1β causes breakdown of the gut epithelium that ...
Breaking Biology News(10 mins):A new synthetic amino acid for an emerging class of drugs 2A new synthetic amino acid for an emerging class of drugs 3Changing global diets is vital to reducing climate change 2Changing global diets is vital to reducing climate change 3Changing global diets is vital to reducing climate change 4The early cost of HIV 2
... at Boulder team working at 16,400 feet in the ... retreating glacier ice can swiftly establish a thriving community ... alpine plants. The discovery is the first to ... one of the most extreme environments on Earth and ...
... choice all too frequently has come down to living ... indoor allergens. Today, The Clorox Company extends its ... Anti-Allergen Fabric Spray, a new product to help manage ... Clorox® Anywhere® Anti-Allergen Fabric Spray denatures dust mite ...
... Humans aren,t the only ones who like fatty foods - ... the Bearded Vulture Study and Protection Group in El Pont ... discard less energy-dense bones and choose only the bones containing ... to its young. His findings will be published this week ...
Cached Biology News:As Andean glacier retreats, tiny life forms swiftly move in, CU-Boulder study shows 2As Andean glacier retreats, tiny life forms swiftly move in, CU-Boulder study shows 3The Clorox Company's new indoor allergen product reduces common indoor allergens up to 90 percent 2Scavenger birds chew the fat 2
(Date:8/29/2014)... 29, 2014 Local veterinarian, Dr. Keith ... are seeking candidates to participate in an investigational study ... The ultimate goal of this study is to determine ... one or two arthritically affected joints can help reduce ... Candidates for the current investigational study must be older ...
(Date:8/29/2014)... August 29, 2014 Intrinsic Imaging, ... certified, GAMP® 5 compliant imaging core lab, announced ... Phase II clinical trial to assess a new ... this trial, Intrinsic Imaging will provide comprehensive imaging ... protocol and charter development, site qualification, site training ...
(Date:8/28/2014)... MA (PRWEB) August 28, 2014 “This kit ... test to screen from 0 to 150 ppb,” said Mark ... is a significant benefit to plant owners and USDA-GIPSA inspection ... and other commodities. Testing can take place in a matter ... only can the plant test the feed and grain before ...
(Date:8/28/2014)... August 28, 2014 The ability for ... culture that will allow individuals to perform at the ... important for employers looking to compete in this post–recession ... embracing this trend, as the sector increasingly focuses on ... company, which will have real results on the organization's ...
Breaking Biology Technology:Burnt Hills Veterinary Hospital Seeks Candidates for an Investigational Study of Stem Cells for Dogs with Arthritis 2Intrinsic Imaging Awarded Phase II Clinical Trial to Assess New Treatment for Non-Hodgkin’s Lymphoma 2Klein Hersh International Leads Philadelphia Area Life Science Industry in Company Culture 2Klein Hersh International Leads Philadelphia Area Life Science Industry in Company Culture 3
... For a biotech company, raising money is a saga that never ... do two things: execute on the timely achievement of key milestones ... of your next financing and where and who the money will ... in for a single round whereas most VCs usually commit for ...
...
... predicts the Alzheimer's disease drug market in ... by 15 percent annually for the next five ... entitled "Global Markets for Alzheimer's Disease Medications 2005," ... in an Alzheimer's drug market that generated more ...
Cached Biology Technology:Financing of biotech companies so far in 2005: A Midwest odyssey 2Financing of biotech companies so far in 2005: A Midwest odyssey 3Financing of biotech companies so far in 2005: A Midwest odyssey 4Financing of biotech companies so far in 2005: A Midwest odyssey 5Alzheimer's drug market to hit $5.5 billion by 2009, study says 2
Chicken polyclonal to YebU ( Abpromise for all tested applications). Antigen: Synthetic peptide, corresponding to amino acids 196-244 of E. coli YebU....
Mouse monoclonal [6911] to E. coli K99 pilus ( Abpromise for all tested applications)....
... Antibody to CRF The ... ovine CRF sequence that it ... fibres are found in the ... brain in colchicine treated 4% ...
... siSolutions siRNA Custom Synthesis ... effective duplex RNA to knockdown ... 21-mers (19 RNA base pairs ... recently-published 27-mers, or other lengths ...
Biology Products: