Navigation Links
A nanoscale window to the biological world
Date:12/20/2012

If the key to winning battles is knowing both your enemy and yourself, then scientists are now well on their way toward becoming the Sun Tzus of medicine by taking a giant step toward a priceless advantage the ability to see the soldiers in action on the battlefield.

Investigators at the Virginia Tech Carilion Research Institute have invented a way to directly image biological structures at their most fundamental level and in their natural habitats. The technique is a major advancement toward the ultimate goal of imaging biological processes in action at the atomic level.

"It's sort of like the difference between seeing Han Solo frozen in carbonite and watching him walk around blasting stormtroopers," said Deborah Kelly, an assistant professor at the VTC Research Institute and a lead author on the paper describing the first successful test of the new technique. "Seeing viruses, for example, in action in their natural environment is invaluable."

The technique involves taking two silicon-nitride microchips with windows etched in their centers and pressing them together until only a 150-nanometer space between them remains. The researchers then fill this pocket with a liquid resembling the natural environment of the biological structure to be imaged, creating a microfluidic chamber.

Then, because free-floating structures yield images with poor resolution, the researchers coat the microchip's interior surface with a layer of natural biological tethers, such as antibodies, which naturally grab onto a virus and hold it in place.

In a recent study in Lab on a Chip, Kelly joined Sarah McDonald, also an assistant professor at the VTC Research Institute, to prove that the technique works.

McDonald provided a pure sample of rotavirus double-layered particles for the study.

"What's missing in the field of structural biology right now is dynamics h
'/>"/>

Contact: Paula Byron
paulabyron@vtc.vt.edu
540-526-2027
Virginia Tech
Source:Eurekalert  

Page: 1 2 3

Related biology news :

1. Nanoscale scaffolds and stem cells show promise in cartilage repair
2. Researchers develop method to grow artificial tissues with embedded nanoscale sensors
3. Engineering research centers awarded $55.5 million to innovate in nanoscale science and engineering
4. New NIH/NHGRI grants to harness nanoscale technologies to cut DNA sequencing costs
5. Salk scientists open new window into how cancers override cellular growth controls
6. Feel-good glass for windows
7. Wireless window sentinel
8. Unraveling biological networks
9. New method for estimating parameters may boost biological models
10. A project to research biological and chemical aspects of microalgae to fuel approach
11. EPA to highlight innovative ways to detect and respond to biological threats
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
A nanoscale window to the biological world
(Date:12/17/2014)... Markets ( http://www.researchandmarkets.com/research/s6qzt5/samsung_galaxy_s5 ) has announced the ... Button Synaptics Fingerprint Sensor Technology Analysis" report to ... Based on a totally different sensing technology ... time a fingerprint sensor in its product. ...
(Date:12/17/2014)... 2014 Research and Markets ( http://www.researchandmarkets.com/research/9zq33j/global_chemical ) ... Sensor Market 2015-2019" report to their offering. ... major trend upcoming in this market is the increasing ... help in recording of patient data for quick and ...
(Date:12/11/2014)... 2014 Research and Markets , ... has announced the addition of the "Biometrics Market ... One major trend emerging in this market ... systems utilize more than one characteristic of an individual ...
Breaking Biology News(10 mins):Samsung Galaxy S5 - Home Button Synaptics Fingerprint Sensor Technology Analysis 2Global Chemical Sensor Market 2015-2019: Key Vendors are Abbott Laboratories, Bayer, Hoffmann La-Roche, Johnson & Johnson, NGK Spark Plugs and Robert Bosch 2Biometrics Market in India 2015-2019: Key Vendors are 3M Cogent, NEC, Safran and Suprema 2
... with genetically engineered mice, Johns Hopkins scientists have interfered with ... high-fat diet. The report, to be published in the ... Sciences online the week of May 1, is based on ... needs to manage body weight. , According to the ...
... Giving antioxidants is recognised as one way of helping ... , The herbal medicine extracted from seeds of ... have antioxidant properties and research published this week in ... significantly lower the amount of sugar bound to haemoglobin ...
... a serious influenza outbreak will do little to hold back ... a study conducted at the UK Health Protection Agency and ... new type of influeza virus appears that causes an illness ... flu. This happened, for example, in 1918, when a flu ...
Cached Biology News:Eat less, weigh more? Enzyme makes lean mice 'susceptible' to dietary fat 2Eat less, weigh more? Enzyme makes lean mice 'susceptible' to dietary fat 3Air travel and pandemic flu 2
(Date:1/22/2015)... Davis, California (PRWEB) January 22, 2015 ... of Accelerator Mass Spectrometry (AMS) services to the pharmaceutical ... PhD has joined the company in the position of ... 30 years of broad and valuable experience in drug ...
(Date:1/22/2015)... NH (PRWEB) January 22, 2015 GEA ... a table top laboratory homogenizer, the PandaPLUS 2000, which ... nanodispersions, nanoemulsions , and cell disruption . This ... dairy products, fruit juices, liquid food, food additives and ...
(Date:1/22/2015)... The laboratory information management systems market is ... of technological advancements due to factors such as rising ... integrate healthcare systems, and increasing government support for adoption ... Key players in the market focus on technological advancements ...
(Date:1/22/2015)... California (PRWEB) January 22, 2015 Pipette.com ... Offer to their comprehensive portfolio of Eppendorf products. ... customers to purchase a Centrifuge 5424/5424 R and receive ... of either Eppendorf Research plus or Eppendorf Reference 2 ...
Breaking Biology Technology:Eckert & Ziegler Vitalea Science appoints Mark Seymour, PhD as Director of Science & Technology 2Eckert & Ziegler Vitalea Science appoints Mark Seymour, PhD as Director of Science & Technology 3GEA Niro Soavi Announces the PandaPLUS 2000 Homogenizer for Processing New Applications for Nanoemulsions and Cell Disruption 2Laboratory Information Management Systems Market is Expected to Reach $1,323.6 Million by 2019 - New Research Report by MarketsandMarkets 2Laboratory Information Management Systems Market is Expected to Reach $1,323.6 Million by 2019 - New Research Report by MarketsandMarkets 3Laboratory Information Management Systems Market is Expected to Reach $1,323.6 Million by 2019 - New Research Report by MarketsandMarkets 4Eppendorf Announces Promotional Bundle Which Includes: Eppendorf Centrifuge 5424, 3-Pack of Pipettes, and Tips - Available Now at Pipette.com 2
... San Francisco, CA, March 18, 2011 Cytokinetics, Incorporated ... in the March 18, 2011 issue of the journal ... by an investigational drug candidate, omecamtiv mecarbil, and the ... for patients with systolic heart failure. This publication ...
... Quest Diagnostics Incorporated (NYSE: DGX ), ... its ColoVantage test has been approved by New York ... in the state. It is believed to be the ... blood specimen to be approved by the state.   ...
... Life Sciences Holdings, Inc. (OTC Bulletin Board: ADLS ... and webcast discussing the Company,s 2010 fourth quarter and full-year ... (EDT). Michael T. Flavin, Ph.D., Chairman & Chief Executive Officer, ... also present an update on the Company. A press release ...
Cached Biology Technology:Cytokinetics announces fundamental research in cardiac myosin activation in the journal Science 2Cytokinetics announces fundamental research in cardiac myosin activation in the journal Science 3New York State Approves the Quest Diagnostics ColoVantage™ Colorectal Cancer Blood Test 2New York State Approves the Quest Diagnostics ColoVantage™ Colorectal Cancer Blood Test 3Advanced Life Sciences to Host 2010 Fourth Quarter and Full-Year Financial Results Conference Call and Webcast 2
... by Stoelting, selects single cells, or clusters, ... time at all, a single cell can ... cell is collected into the pipette, and ... a microtiter plate. Quixells unique aspiration and ...
... for genome-wide microRNA expression profiling and ... Paraflo microfluidic on-chip synthesis platform. These ... our comprehensive microRNA Expression Profiling Service. ... Viruses microRNA Microarray contains all known ...
... of Agilent analytical solutions is the 6890N ... (LAN) allows you to share business and ... decision making. Just as its 6890 GC ... and performance needed for research and method ...
The novel and unique HCTplus delivers unmatched information-rich data-dependent LC/MSn data for todays challenge in proteomics and metabonomics work....
Biology Products: