Navigation Links
A mother's salt intake could be key to prenatal kidney development
Date:7/6/2011

Bethesda, Md. (July 6, 2011) A new animal study from Europe has drawn an association between pregnant mothers' sodium intake and their newborn's kidney development. Among the most significant aspects of the study's findings is that either too much or too little salt during pregnancy had an adverse effect on the prenatal development of the offspring's kidneys. The consequence of such disruption can lead to high blood pressure in later years.

These are the conclusions reached in the study, "Both High and Low Maternal Salt Intake in Pregnancy Alters Kidney Development in the Offspring," conducted by Nadezda Koleganova, Grzegorz Piecha, Annett Mller, Monika Weckbach, Peter Schirmacher, and Marie-Luise Gross-Weissmann, Eberhard Ritz and Luis Eduardo Becker, all with the University of Heidelberg in Heidelberg, DE; and Jens Randel Nyengaard of the University of Aarhus, Aarhus, DK. Their study is published in the online edition of the American Journal of Physiology--Renal Physiology.

Background

This research builds upon past studies that recognize that excessive salt intake causes secretion of endogenous cardiotonic steroids such as marinobufagenin (MBG). For the pregnant female, this can be harmful since high concentrations of MBG are correlated to low birth-weight and higher blood pressure in the offspring.

Previous research has also linked high blood pressure with a low nephron number, critical because the nephron is the basic structural and functional unit of the kidney. The nephron eliminates wastes from the body, regulates blood volume and blood pressure, controls levels of electrolytes and metabolites, and regulates blood pH. Its functions are vital to life and are regulated by the endocrine system.

Methodology

Sprague-Dawley rats were fed low, intermediate or high sodium diets during pregnancy and lactation. The litters were standardized to identical size at birth with 1:1 male to femal
'/>"/>

Contact: Donna Krupa
dkrupa@the-aps.org
703-634-7209
American Physiological Society
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. New mothers can learn a lot from watching their babies
2. Parenting stress affects new mothers’ postpartum lifestyle
3. Preterm mothers milk contains less antioxidants than mothers completing their gestation
4. Mothers diets have biggest influence on children eating healthy
5. New report suggests why risk for sudden infant death syndrome is greater in babies of mothers who smoke
6. Successful mothers get help from their friends: Dolphin study
7. Discus fish parent young like mammalian mothers
8. Black mothers cite lack of desire as top reasons for not breastfeeding
9. About 94 percent of breastfeeding mothers do not follow a proper diet
10. Giving DHA supplements to breastfeeding mothers
11. HPV vaccination more likely if mothers approve
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/7/2014)... , November 6, 2014 Leading ... for better mobile security revolutionizing online transactions.  Companies in focus ... Holdings Ltd. (NYSE: BABA ), Google Inc. (NASDAQ: ... ), eBay Inc. (NASDAQ: EBAY ) and MasterCard ... NXTD and NXTDW), a biometric authentication company focused on ...
(Date:11/6/2014)... metastasis, yet progress in preventing and treating migratory ... particularly challenging to design drugs that work against ... biology at Harvard Medical School. , "Unfortunately, ... metastasized." , Gujral and colleagues have now identified ... understand how metastasis begins. Their findings may also ...
(Date:11/6/2014)... Medicine, Inc, a Baltimore-based bioinformatics company focused on ... a research collaboration with the international leader in ... CSBR). , "There are many companies utilizing advances ... TumorGraft technology is unique in a way that ... vast amounts of valuable data. Our bioinformatic analysis ...
Breaking Biology News(10 mins):Universal Authentication Methods Provide More Secure Operations for Biometrics Devices - Company Joins FIDO Alliance for Consumer Protection 2Universal Authentication Methods Provide More Secure Operations for Biometrics Devices - Company Joins FIDO Alliance for Consumer Protection 3Universal Authentication Methods Provide More Secure Operations for Biometrics Devices - Company Joins FIDO Alliance for Consumer Protection 4Universal Authentication Methods Provide More Secure Operations for Biometrics Devices - Company Joins FIDO Alliance for Consumer Protection 5Universal Authentication Methods Provide More Secure Operations for Biometrics Devices - Company Joins FIDO Alliance for Consumer Protection 6Migration negation 2Migration negation 3Insilico Medicine, Inc announces research collaboration with Champions Oncology, Inc 2
... European Molecular Biology Laboratory (EMBL) have generated a digital ... a vertebrate. With a newly developed microscope scientists could ... first 24 hours in the life of a zebrafish. ... of the embryo. The study, published in the current ...
... The Indonesian government and World Wildlife Fund (WWF) today ... and critical ecosystems of Sumatra, an Indonesian island that ... endangered forests. The historic agreement represents the first-ever ... commitment has been endorsed by governors of all provinces ...
... and Infectious Diseases (NIAID), part of the National Institutes ... be up to $68.7 million to establish programs in ... institutions. Scientists at each facility will apply novel techniques ... (SARS), tuberculosis and influenza. Systems biology is the ...
Cached Biology News:Digital zebrafish embryo provides the first complete developmental blueprint of a vertebrate 2Saving Sumatra: Indonesia reaches historic agreement 2New Systems Biology Awards enable detailed study of microbes 2
(Date:11/26/2014)... The ETC (Emerging Technology Centers) http://www.etcbaltimore.com , ... that applications for AccelerateBaltimore™ (AB) 2015 program will ... a big idea?,” asked ETC’s President Deb Tillett. ... AccelerateBaltimore helps you and your big idea go ... Interested game changers with “big ideas” should ...
(Date:11/26/2014)... TX (PRWEB) November 25, 2014 Continuing ... skincare products, earned three prestigious MarCom Awards for outstanding ... Nerium received a Platinum MarCom Award, the organization’s top ... Event in St. Louis held in April of this ... more than 14,000 attendees. Additionally, Nerium was awarded a ...
(Date:11/26/2014)... WILMINGTON, DE (PRWEB) November 26, 2014 ... MPN Heroes recognition reception on December 5, 2014, in ... annual meeting. The MPN Heroes event will honor clinicians, ... the field of myeloproliferative neoplasms (MPNs). , Special ... will discuss his family's cancer journey at the reception. ...
(Date:11/26/2014)... , Nov. 25, 2014  Roka Bioscience, Inc. (NASDAQ: ... providing advanced testing solutions for the detection of foodborne pathogens, ... at the Piper Jaffray  26 th Annual Healthcare Conference ... be held at The New York Palace in ... presentation, material information concerning the Company, its operations, strategies and ...
Breaking Biology Technology:AccelerateBaltimore Applications to Close in 6 Days 2AccelerateBaltimore Applications to Close in 6 Days 3Nerium International™ Wins One Platinum, Two Gold MarCom Awards 2CURE Magazine and Incyte to Honor MPN Heroes 2CURE Magazine and Incyte to Honor MPN Heroes 3CURE Magazine and Incyte to Honor MPN Heroes 4Roka Bioscience to Present at the Piper Jaffray Healthcare Conference 2
Determin interaction of your protein with Echelons lipids...
Identify and characterize Phosphoinositide (PI(4,5)P2) binding...
... Moto Alpha unit with motorized heated lid and ... is useful for microarrays and chips. The four ... The sealing force of the motorized lid is ... give repeatable results. This interchangeable Moto Alpha unit ...
... Anti-Krueppel-like factor 15 (KLF15) KLF15 ... is found abundantly expressed in the liver, ... #: NP_054798 Specificity: Polyclonal antibody produced ... corresponding to a region of human KLF15 ...
Biology Products: