Navigation Links
A history lesson from genes
Date:1/9/2013

When Charles Darwin first sketched how species evolved by natural selection, he drew what looked like a tree. The diagram started at a central point with a common ancestor, then the lines spread apart as organisms evolved and separated into distinct species.

In the 175 years since, scientists have come to agree that Darwin's original drawing is a bit simplistic, given that multiple species mix and interbreed in ways he didn't consider possible (though you can't fault the guy for not getting the most important scientific theory of all time exactly right the first time). Using a tree-like structure is a great way to show the history of the evolution of a species, or its phylogeny. But it's not so great for showing the population history of groups within a single species, such as humans, who can move around and interbreed with each other.

Jonathan Pritchard, PhD, professor in the department of human genetics, studies the nature of these human genetic variations by combining methods from evolutionary biology and statistics. Intrigued by recent research on the Neanderthal genome that suggests more interbreeding with Homo sapiens than previously thought, Pritchard wanted to develop a general method for estimating gene flow between different groups within the same species over time. In a recent paper published in PLOS Genetics, he and Joseph Pickrell, a former University of Chicago researcher now at Harvard, described a software model they developed that can infer the history of population splits and mixtures within a species based on modern DNA.

"If you try to make a tree of population histories within a species, there's always the possibility that you've got genes flowing from one branch to another," Pritchard said. "The populations can interbreed, so if they're geographically together or if there's movement from one place to another, then this tree representation is not necessarily going to be a good way of representing history
'/>"/>

Contact: Matt Wood
matthew.wood@uchospitals.edu
773-702-5894
University of Chicago Medical Center
Source:Eurekalert  

Page: 1 2 3

Related biology news :

1. Chinese scientists discover evidence of giant pandas population history and local adaptation
2. Reading history through genetics
3. New test adds to scientists understanding of Earths history, resources
4. Recent studies bring fossils and genes together to piece together evolutionary history
5. King Richard III search in new phase after discovery has potential to rewrite history
6. New Nature study illuminates 55 million years of the carbon cycle and climate history
7. Geologys Mystery Interval, the Great Deepening, and the largest kill-off in Earth history
8. Bringing natural history collections out of the dark
9. Short stretches of piRNA evaluate cells genetic history
10. IU role in Human Microbiome Project exposes battle history between bacteria, viruses in human body
11. New report puts real numbers behind history of oyster reefs
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
A history lesson from genes
(Date:11/21/2014)... 2014 C-Labs LLC, a leading provider of ... (IoT), today announced the appointment of John Traynor ... a strategic advisor to the firm, Mr. Traynor will ... is based out of the C-Labs office in ... Chris Muench , Chief Executive Officer. Photo ...
(Date:11/18/2014)... Nov. 18, 2014   EyeLock Inc. , ... and MorphoTrust USA (Safran), a leading ... announced a strategic partnership to offer comprehensive biometric ... administration (MVA), airport screening and financial services markets. ... MorphoTrust serves consumers through a nationwide network of ...
(Date:11/7/2014)... Debra Auguste, associate professor, biomedical engineering, in the ... of New York, have identified a molecule that ... the most aggressive forms of breast cancer. , ... mortality rate owing to aggressive proliferation and metastasis ... Professor Auguste,s team, discovered the overexpression of intercellular ...
Breaking Biology News(10 mins):C-Labs Names Former Microsoft and Bsquare Executive as Chief Operating Officer 2EyeLock, MorphoTrust Form Strategic Partnership to Pursue Commercial Enterprise Deployments 2EyeLock, MorphoTrust Form Strategic Partnership to Pursue Commercial Enterprise Deployments 3
... School of Medicine have found that new disease pathways ... 1 Gaucher disease, a rare genetic disorder in which ... liver/spleen enlargement, osteoporosis, bone pain, and increased risk of ... could lead to less expensive and more effective ways ...
... the cure for a fungus and parasite that affects millions ... of Missouri Chemistry Professor John Tanner would be the forensic ... model that could eventually solve the crime. Tanner, who also ... joined forces with Pablo Sobrado, an assistant professor of biochemistry ...
... CHAMPAIGN, Ill. University of Illinois chemists have ... in shoe bombs. It could lead to inexpensive, easy-to-use ... elsewhere. Triacetone triperoxide (TATP) is a high-powered explosive ... bombing attempts. TATP is easy to prepare from readily ...
Cached Biology News:Cheaper, more effective treatment of type 1 Gaucher disease possible 2X-ray diffraction may play key role in stopping 'kissing bug,' fungus 2Sniffing out shoe bombs: A new and simple sensor for explosive chemicals 2
(Date:11/22/2014)... 2014 Respiratory therapy students will ... management of life-like respiratory ailments using the latest ... Grand Rapids-based, Michigan Instruments Inc. developers of the ... the respiratory simulation units to the pro-gram, which ... and Muskegon Community College are collaborating to offer ...
(Date:11/21/2014)... USA (PRWEB) November 19, 2014 The ... our lives was shared with more than 200 primary ... postgraduate students from the University of Otago Physics Department ... . The Otago students, members of the university’s OSA/SPIE ... Zealand in early September, giving children from small, rural ...
(Date:11/21/2014)... NY (PRWEB) November 20, 2014 The ... now available as an open access journal featuring the ... infrared fluorescent proteins to preserve photoresponsiveness in the retina ... Two-color fluorescent in situ hybridization using chromogenic substrates in ... for DNA, RNA, and protein electrophoresis , ...
(Date:11/21/2014)... , Nov. 20, 2014 Polaris Group ... dosed in its Phase 1 trial of ADI-PEG ... the treatment of malignant pleural mesothelioma (MPM) and ... conducting clinical trials on ADI-PEG 20, both as ... the treatment of several other indications, including breast ...
Breaking Biology Technology:Michigan Instruments Donates Two Respiratory Simulation Training and Test Lung (TTL) Devices to Grand Valley State University 2Michigan Instruments Donates Two Respiratory Simulation Training and Test Lung (TTL) Devices to Grand Valley State University 3Optics and photonics outreach programs share science, spark fascination with light 2Optics and photonics outreach programs share science, spark fascination with light 3BioTechniques: The International Journal of Life Science Methods Announces the Publication of the November 2014 Issue—Available in Print and Online 2BioTechniques: The International Journal of Life Science Methods Announces the Publication of the November 2014 Issue—Available in Print and Online 3Polaris Group Announces Treatment of First Patient in Phase 1 Study of ADI-PEG 20 plus Pemetrexed and Cisplatin in Malignant Pleural Mesothelioma And Non-Squamous Non-Small Cell Lung Carcinoma 2
... , June 1 /PRNewswire/ -- Pioneer Surgical Technology, ... follow up on the NuBac IDE feasibility study patients was presented at ... of Spine Surgery (SAS) in New Orleans by Domagoj ... , , ...
... June 1 /PRNewswire-FirstCall/ - Oncolytics Biotech Inc. ... has received approval from the Belgian Federal Agency for ... 3 trial examining REOLYSIN in combination with paclitaxel and ... This is the same trial that was agreed to ...
... BOZEN, Sud-Tirol, Italy , May ... joint venture Health Robotics South East Asia Ltd.,scored two ... to deliver CytoCare-made accurate and sterile,oncology patient doses in ... Health,Robotics, CytoCare is the first and only robot in ...
Cached Biology Technology:Two-Year Follow up Data of NuBac® IDE Feasibility Study Was Presented at SAS Meeting 2Oncolytics Biotech(R) Inc. Receives Approval from Belgium FAMHP to Conduct Phase 3 Trial for REOLYSIN(R) in Head and Neck Cancers 2Oncolytics Biotech(R) Inc. Receives Approval from Belgium FAMHP to Conduct Phase 3 Trial for REOLYSIN(R) in Head and Neck Cancers 3Oncolytics Biotech(R) Inc. Receives Approval from Belgium FAMHP to Conduct Phase 3 Trial for REOLYSIN(R) in Head and Neck Cancers 4Health Robotics South East Asia Wins two key Cancer Therapy Outsourcing Projects in Malaysia and Thailand 2Health Robotics South East Asia Wins two key Cancer Therapy Outsourcing Projects in Malaysia and Thailand 3