Navigation Links
23andMe and ALSPAC identify 16 new genetic associations for pollen, dust-mite and cat allergies
Date:7/2/2013

te and cat allergies for which comparable data was available both in the 23andMe research community and in a cohort from the Avon Longitudinal Study of Parents and Children (ALSPAC). Data from both organizations was then included in a genome-wide association meta-analysis.

"Allergy is an important component of many diseases, including asthma, eczema and hay fever, which together account for a huge burden on patients and the health services." said professor John Henderson of ALSPAC. "This is a very exciting time for allergy research. Genetic discoveries have identified specific pathways of allergy development that are not shared with allergic diseases like asthma. Understanding these pathways could lead to eventual development of drugs that cure or prevent allergy rather than just suppressing its symptoms."

"One of the key features of this work is the demonstration that with a suitably sized study, the analysis of medically relevant questionnaire data alongside genetic variation has the potential to yield important information concerning the underlying biology of a complex outcome," said Dr. Nic Timpson of ALSPAC. "Indeed, through this collaborative interaction with colleagues from EAGLE where specific tests of allergic sensitization were available, we were able to independently replicate many of the findings made here."

Also published on June 30, 2013 in Nature Genetics was a companion study called, "Meta-Analysis of Genome-Wide Association Studies Identifies 10 Loci Influencing Allergic Sensitization". This study had similar methodology to the 23andMe/ALSPAC study but was conducted by the Early Genetics and Lifecourse Epidemiology research cohort (EAGLE) using clinically defined data instead of self-reported data. This provided the opportunity to compare results of self-reported data to study results based on clinically defined data. The results from the studies were generally very consistent, highlighting many of the same genes
'/>"/>

Contact: Kendra Brogden
kbrogden@wcgworld.com
415-658-9765
23andMe Inc.
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. 23andMe identifies multiple genetic factors impacting development of nearsightedness
2. 23andMes Ancestry Composition reveals peoples ancestral origins going back 500+ years
3. 23andMe scientists receive more than $500,000 in National Institutes of Health funding
4. 23andMe Names Christine Castro, Neil Rothstein and Jonathan Ward to Leadership Positions
5. 23andMe opens its API to developers
6. 23andMe contributes to genetic discoveries related to male pattern baldness
7. 23andMe identifies 5 significant genetic associations for hypothyroidism
8. Scientists identify promising antiviral compounds
9. NIH to fund collaborations with industry to identify new uses for existing compounds
10. Study helps managers identify regions with multiple threat potential, including wildfires
11. Iris Biometrics Leader EyeLock Joins the FIDO Alliance to Help Identify More Secure Replacement for Usernames and Passwords
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/31/2014)... "electronic-nose" for sniffing the highly infectious bacteria C. ... has been developed by a team at the University ... team has demonstrated that it is possible to identify ... would lead to rapid diagnosis of the condition., What ... possible to identify different strains of the disease simply ...
(Date:8/31/2014)... Over the past several decades, malaria diagnosis has changed very ... technician smears the blood across a glass slide, stains it ... the Plasmodium parasite, which causes the disease. This approach gives ... blood an important measure of disease severity but ... , A research team from the Singapore-MIT Alliance for Research ...
(Date:8/29/2014)... University of Texas Medical Branch at Galveston has gone on ... completely protect monkeys against a lethal dose of Ebola virus ... the disease is severe. , Thomas Geisbert, professor of microbiology ... discussing advances in Ebola treatment research. The filoviruses known as ... of pathogens, with fatality rates of up to 90 percent. ...
Breaking Biology News(10 mins):Scientists develop 'electronic nose' for rapid detection of C. diff infection 2A new way to diagnose malaria 2A new way to diagnose malaria 3Leading Ebola researcher at UTMB says there's an effective treatment for Ebola 2
... first experimental evidence that birds can be deceived by camouflage ... today in Nature [3 March 2005]. , The idea that ... rapidly adopted by many armies as long ago as the ... colouration' has long been used to explain how insects such ...
... that radio-tracking could be affecting the animals they ... in the British Ecological Society's Journal of Applied ... with a "dramatic shift" in the sex ratio ... assumption that radio-tracking does not fundamentally affect the ...
... Blackburn is responsible for collecting and storing thousands of ... -- to make sure there's enough genetic material to ... deals with important livestock such as Holstein cattle and ... who is the coordinator of the animal section at ...
Cached Biology News:Radio-tracking associated with 'dramatic shift' in water vole sex ratio 2Making Sure Sacred Sheep Don't Become Extinct 2
(Date:8/31/2014)... Available spectra is similar for ... and cultivation of a wide range of plants. ... with proven patented and pending wide spectrum technology. ... in critical applications in contrast to growth spectra ... customers have a large variety of differently sized ...
(Date:8/29/2014)... Electronic circuits are based on electrons, but one of ... photonic circuits, i.e. circuits based on light (photons) instead ... to create a stream of single photons and control ... sorts of attempts to achieve this control, but now ... creating a steady stream of photons emitted one at ...
(Date:8/29/2014)... Hills, NY (PRWEB) August 29, 2014 ... Burnt Hills Veterinary Hospital are seeking candidates to participate ... dogs with osteoarthritis. The ultimate goal of this ... donor stem cells into one or two arthritically affected ... treated joints. , Candidates for the current investigational ...
(Date:8/28/2014)... USA (PRWEB) August 28, 2014 SPIE ... of Physics and Optical Science and Director of the ... of North Carolina at Charlotte, and co-founder and Chairman ... to serve as the 2015 Vice President of SPIE, ... 2014 President Philip Stahl announced recent election results at ...
Breaking Biology Technology:Breakthrough in light sources for new quantum technology 2Burnt Hills Veterinary Hospital Seeks Candidates for an Investigational Study of Stem Cells for Dogs with Arthritis 2Glenn Boreman, UNC Professor and Plasmonics Co-Founder, Elected to SPIE Presidential Chain 2
... Previous Quarter, NEW YORK, May 15 ... biosensor and microprocessor technologies for,use in portable monitoring ... ended March 31, 2008., Gross revenues for ... quarter 2007 gross revenues. The increase in revenues ...
... YORK, May 15 American Oriental,Bioengineering, Inc. (NYSE: ... health through the development, manufacture and commercialization,of a ... ("OTC") products in,China, today released the following statement ... with the many victims of China,s earthquake and ...
... 15 /Xinhua-PRNewswire-FirstCall/ -- Huifeng Bio-,Pharmaceutical Technology, Inc. ... producer of plant extracts and pharmaceutical raw ... production, today,announced that there was no damage ... the Sichuan Earthquake., Immediately following the ...
Cached Biology Technology:SPO Medical Reports First Quarter 2008 Results 2SPO Medical Reports First Quarter 2008 Results 3American Oriental Bioengineering Comments on Earthquake 2Huifeng Bio-Pharmaceutical (HFGB) Announces No Earthquake Related Damage to Facilities 2
BD Primaria 35 mm Cell Culture Dish with Easy-Grip design, surface-modified polystyrene for enhanced cell culture. (20/sp, 200/ca) Packaging: 20 / sleeve, 500 / case ...
... is a software package that provides ... for custom buffer creation, set-up of ... crystallization trials. The software helps crystallographers ... automated protein crystallography: ...
The PROTEAN II slab gel casting stand is a component of the PROTEAN II XL and xi casting apparatus. It is supplied with gaskets....
Mouse monoclonal [H4B4] to LAMP2 - Lysosome Marker (Phycoerythrin) ( Abpromise for all tested applications). entrezGeneID: 3920 SwissProtID: P13473...
Biology Products: