Navigation Links
23andMe and ALSPAC identify 16 new genetic associations for pollen, dust-mite and cat allergies
Date:7/2/2013

te and cat allergies for which comparable data was available both in the 23andMe research community and in a cohort from the Avon Longitudinal Study of Parents and Children (ALSPAC). Data from both organizations was then included in a genome-wide association meta-analysis.

"Allergy is an important component of many diseases, including asthma, eczema and hay fever, which together account for a huge burden on patients and the health services." said professor John Henderson of ALSPAC. "This is a very exciting time for allergy research. Genetic discoveries have identified specific pathways of allergy development that are not shared with allergic diseases like asthma. Understanding these pathways could lead to eventual development of drugs that cure or prevent allergy rather than just suppressing its symptoms."

"One of the key features of this work is the demonstration that with a suitably sized study, the analysis of medically relevant questionnaire data alongside genetic variation has the potential to yield important information concerning the underlying biology of a complex outcome," said Dr. Nic Timpson of ALSPAC. "Indeed, through this collaborative interaction with colleagues from EAGLE where specific tests of allergic sensitization were available, we were able to independently replicate many of the findings made here."

Also published on June 30, 2013 in Nature Genetics was a companion study called, "Meta-Analysis of Genome-Wide Association Studies Identifies 10 Loci Influencing Allergic Sensitization". This study had similar methodology to the 23andMe/ALSPAC study but was conducted by the Early Genetics and Lifecourse Epidemiology research cohort (EAGLE) using clinically defined data instead of self-reported data. This provided the opportunity to compare results of self-reported data to study results based on clinically defined data. The results from the studies were generally very consistent, highlighting many of the same genes
'/>"/>

Contact: Kendra Brogden
kbrogden@wcgworld.com
415-658-9765
23andMe Inc.
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. 23andMe identifies multiple genetic factors impacting development of nearsightedness
2. 23andMes Ancestry Composition reveals peoples ancestral origins going back 500+ years
3. 23andMe scientists receive more than $500,000 in National Institutes of Health funding
4. 23andMe Names Christine Castro, Neil Rothstein and Jonathan Ward to Leadership Positions
5. 23andMe opens its API to developers
6. 23andMe contributes to genetic discoveries related to male pattern baldness
7. 23andMe identifies 5 significant genetic associations for hypothyroidism
8. Scientists identify promising antiviral compounds
9. NIH to fund collaborations with industry to identify new uses for existing compounds
10. Study helps managers identify regions with multiple threat potential, including wildfires
11. Iris Biometrics Leader EyeLock Joins the FIDO Alliance to Help Identify More Secure Replacement for Usernames and Passwords
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/10/2015)... , March 10, 2015 Transforming ... "Personalized Medicine in Human Space Flight" ... Thomas J. Goodwin , Ph.D. was recently featured by ... past two years. Specifically, "Personalized Medicine in ... scientific papers published in 2013 and 2014 from Springer ...
(Date:3/4/2015)... 2015 Research and Markets ( ... "Global Biometrics Market Forecast and Opportunities, 2020" ... market for biometric authentication systems is projected to ... 2020 The driving forces for this ... government projects and constant development in technology. In ...
(Date:3/2/2015)... Lithuania , March 2, 2015   Neurotechnology ... technologies, today introduced the SentiGaze Software Development Kit ... to create applications that use off-the-shelf webcams to track ... user gazes at a monitor. Heatmaps can be used ... the effectiveness of online advertising. The SDK can also ...
Breaking Biology News(10 mins):"Personalized Medicine in Human Space Flight" Listed Among Most Influential Papers of 2013 and 2014 2Global Biometrics Market Forecast and Opportunities, 2020 2Global Biometrics Market Forecast and Opportunities, 2020 3Neurotechnology Releases SentiGaze SDK for Eye Movement Tracking Using Ordinary Webcams 2Neurotechnology Releases SentiGaze SDK for Eye Movement Tracking Using Ordinary Webcams 3
... In evaluating the bioactive compounds of Illinois blueberry ... compounds that inhibit enzymes responsible for carbohydrate absorption and ... help people with diabetes decrease their blood sugar. ... that would optimize the inhibition of the alpha-amylase and ...
... Philadelphia, PA, August 20, 2012 The more that ... The same can be said about the genetics and ... disease, mutation of a single gene predictably produces a ... to Mendelian disorders, understanding bipolar disorder has been extremely ...
... Hillel was named the 2012 recipient of the World ... have advanced human development by improving the quality, quantity, ... Hillela more than 50-year member of the Soil Science ... the 2012 International Annual Meetings of the American Society ...
Cached Biology News:Drink made from berry wine may provide tasty drug for diabetes 2Making sense out of the biological matrix of bipolar disorder 2World Food Prize winner among speakers at agronomy, crop and soil science societies meetings 2World Food Prize winner among speakers at agronomy, crop and soil science societies meetings 3
(Date:3/26/2015)... March 26, 2015 PAREXEL International ... clinical research organization , announced today ... agreement to acquire all of the business ... leading provider of specialized pharmacovigilance services, based ... collection, detection, assessment, monitoring, and prevention of ...
(Date:3/26/2015)... 26, 2015 Ale Gicqueau, Founder and ... of Clinical Affairs at Align Technology, on “ Conducting ... upcoming ACRP 2015 Global Conference and Exhibition on April ... , During the poster presentation, Ale Gicqueau and ... running a Postmarket Registry, the requirements and resources to ...
(Date:3/25/2015)... MN (PRWEB) March 26, 2015 Agnition ... upcoming episode of American Farmer, airing for the first ... The segment of American Farmer will explore the extremely ... provides crop producers with a patented Microbial Catalyst™ technology ... and greater yields. The segment will air again on ...
(Date:3/25/2015)... 25, 2015 The surging prevalence ... have fuelled social media growth, with over 50% ... in social networking. Insurance companies are making use ... clients and promote a diversity of their services ... increasingly exploiting social networking services as part of ...
Breaking Biology Technology:PAREXEL Announces Execution of Definitive Agreement to Acquire Quantum Solutions India, Strengthening Leadership In Pharmacovigilance Services 2PAREXEL Announces Execution of Definitive Agreement to Acquire Quantum Solutions India, Strengthening Leadership In Pharmacovigilance Services 3PAREXEL Announces Execution of Definitive Agreement to Acquire Quantum Solutions India, Strengthening Leadership In Pharmacovigilance Services 4Clinovo Presents at ACRP 2015 in Salt Lake City, Utah on April 25th-28th 2Clinovo Presents at ACRP 2015 in Salt Lake City, Utah on April 25th-28th 3Agnition to be Featured In Upcoming Episode of American Farmer on RFD-TV 2Social Media Role in Global Insurance Industry Examined by Timetric in New Market Research Report Published at MarketPublishers.com 2Social Media Role in Global Insurance Industry Examined by Timetric in New Market Research Report Published at MarketPublishers.com 3
... wholly owned subsidiary of British company Innovative Carbon Limited today ... 10th April to 13th. , Graphene, a sheet of carbon ... wonder material. First isolated at Manchester University in 2004, ... race has been on to produce it commercially. To ...
... April 6, 2012 Arteriocyte, a leading biotechnology ... Massachusetts announced today approval from the Food and ... clinical trial using its Magellan MAR01™ technology in ... Device Exemption (IDE 15013) allows Arteriocyte and its ...
... 2012  GenVec, Inc. (NASDAQ:   GNVC) announced publication ... vectors circumvent neutralizing antibodies in order to generate ... published online in PloS ONE, and can be ... "Modification of Ad5 Hexon Hypervariable Regions Circumvents Pre-existing ...
Cached Biology Technology:UK company to demonstrate their commercially effective graphene production process 2Arteriocyte Receives FDA Approval to Initiate Compartment Syndrome Trial for Amputation Prevention Focused on Wounded Warriors 2Arteriocyte Receives FDA Approval to Initiate Compartment Syndrome Trial for Amputation Prevention Focused on Wounded Warriors 3GenVec Announces Research on Improved Vaccine Vectors 2GenVec Announces Research on Improved Vaccine Vectors 3
Apoptosis Detection Systems and Reagents...
...
DAPI: 4', 6-Diamino-2-phenylindole dihydrochloride. Antifade Solution: p-Phenylenediamine and glycerol in PBS solution. 0.4g/mL DAPI suspended in Antifade....
Anti-Mouse Qa.m8, Ascites (Clone 5035-24.1) (mouse IgG3)...
Biology Products: