Navigation Links
2 neuroscientists from Cold Spring Harbor Laboratory awarded 'transformative' NIH grants
Date:9/24/2009

ogical and neuropsychiatric disorders."

The current proposal arose out of planning work in the Brain Architecture Project, undertaken by Mitra with initial funding from the W. M. Keck Foundation and involving important collaborations and contributions from Professor Larry Swanson of the University of Southern California and Jason Bohland, Ph.D., of CSHL, among others. Some of the early discussions took place at meetings Mitra organized over the last several years at CSHL's Banbury Center.

"We hope that the current project will be the seed for a larger community-wide effort for brain-wide circuit mapping across species, enabling comparative studies," said Mitra. "It is greatly encouraging that the NIH, in awarding this generous grant, has taken a leadership role in this area."

Dubnau: Tracing how brain proteins are regulated

Every neuron in the brain forms a complex web of fibers that make connections with countless other neurons. The brain must somehow maintain and control each of these connections by precisely regulating the synthesis or delivery of many different proteins to each of the neural connection points, called synapses. Geneticists already know a great deal about how cells control the quantity of each RNA synthesized ("transcribed") in the nucleus. But these RNA molecules each carry instructions beyond the nucleus, to direct the synthesis of a particular protein. Much less is known about how the translation of each RNA into a given protein is precisely controlled at each neuronal synapse.

Josh Dubnau's "transformative" project addresses an important gap in knowledge: about how this fundamental step in the conversion of genetic information -- its "translation" from RNA to protein -- is regulated in neurons, the ubiquitous cells of the brain whose dense web of connections underlie its capacity to perform sophisticated functions such as forming and storing memories.

"Every neuron in the bra
'/>"/>

Contact: Peter Tarr
tarr@cshl.edu
516-367-8455
Cold Spring Harbor Laboratory
Source:Eurekalert

Page: 1 2 3 4

Related biology news :

1. Caltech neuroscientists find brain region responsible for our sense of personal space
2. Neuroscientists discover long-term potentiation in the olfactory bulb
3. Bipolar disorder genes, pathways identified by Indiana University neuroscientists
4. Advertisers, neuroscientists trace source of emotions in brain
5. Early spring time for Edinburgh? Study predicts effect of global warming on spring flowers
6. Methods for gene transfer in stem cells featured in Cold Spring Harbor Protocols
7. Spring cold snap helps with stream ecosystem research
8. Springer to collaborate with the Human Genome Organization
9. Springer launches SpringerImages
10. Battle of the sexes benefits offspring, says research
11. Bisphenol A exposure in pregnant mice permanently changes DNA of offspring
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/6/2015)... 2015  Today, U.S. Congressman Mike Honda ... to learn firsthand how Silicon Valley technologies can ... a world leader in multi-factor identity management and ... federal agencies and commercial organizations achieve new levels ... "The vast majority of network breaches can be ...
(Date:8/5/2015)... According to a new market ... Services, Vertical (BFSI, Airport, IT & Telecom, Utilities, Education, ... to 2020", published by MarketsandMarkets, defines and segments the ... segments. The global PIAM Market is estimated to grow ... 2019, at a CAGR of 14.9 % from 2014 ...
(Date:8/4/2015)... , Aug. 04, 2015 ... ) has announced the addition of the ... Software, and Service), Sub-Segment (Computer Forensics, Network ... Tool Types, Service, Vertical and Region - ... their offering. By Component (Hardware, ...
Breaking Biology News(10 mins):Rep. Honda to Visit Crossmatch in Redwood City 2Physical Identity and Access Management Market Worth $546.2 Million by 2019 2Physical Identity and Access Management Market Worth $546.2 Million by 2019 3Physical Identity and Access Management Market Worth $546.2 Million by 2019 4Digital Forensics Market - The Market Represents a Compound Annual Growth Rate (CAGR) of 11.3% From 2015 to 2020 2
... A destructive spring freeze that chilled the eastern United States ... poses to plants and crops, according to a paper just ... a team from the Department of Energy,s Oak Ridge National ... in on an ill wind. Plants had been sending out ...
... Dr. Joseph Lipsick (Stanford University) and colleagues demonstrate that ... tumor suppressor gene function together in the Drosophila MMB/dREAM ... Drosophila MMB/dREAM includes proteins encoded by the Myb oncogene ... well as the E2F2 protein which itself binds to ...
... is available in German . , Iron ... component of hemoglobin, the substance that makes our blood red ... cause heavy damage; it is thought that iron deposits in ... as Parkinsons, Huntington s, and Alzhiemers. A malfunction of the ...
Cached Biology News:Killer freeze of '07 illustrates paradoxes of warming climate 2Rusty worms in the brain 2
(Date:8/27/2015)... Aug. 27, 2015 The National Necrotizing ... eyes—and life—were saved by doctors at Vanderbilt University Hospital ... NNFF, NovaBay Pharmaceuticals and Dr. John Crew , ... at Seton Medical Center in Daly City, ... a breakthrough approach, pioneered by Dr. Crew, that had ...
(Date:8/27/2015)... 2015 HUYA Bioscience International (HUYA) today announced the ... Society of HTLV-1, held this week at the University ... the Society is to promote research on HTLV-1 and ... technology and research related to these fields to advance ... is proud to support this prestigious conference," said ...
(Date:8/27/2015)... ... August 27, 2015 , ... METTLER TOLEDO's web-based EasyFinder™ ... product choices to a manageable shortlist of bench and floor scales and terminals. ... fit best with the customer’s industry and application. , Side-by-side product comparisons ...
(Date:8/26/2015)... ... August 26, 2015 , ... MediVet ... a second US laboratory is to open in Manhattan, Kansas in early October, ... and long-term growth of research and development through collaboration with researchers from Kansas ...
Breaking Biology Technology:Patient's Life and Eyes Saved from Gruesome Flesh-Eating Infection Consuming Her Face 2Patient's Life and Eyes Saved from Gruesome Flesh-Eating Infection Consuming Her Face 3HUYA Bioscience International Sponsors Japan Society Of HTLV-1 Annual Meeting 2HUYA Bioscience International Sponsors Japan Society Of HTLV-1 Annual Meeting 3HUYA Bioscience International Sponsors Japan Society Of HTLV-1 Annual Meeting 4METTLER TOLEDO Updates Online Scale Selection Tool 2MediVet Biologics Animal Health Secures Additional Laboratory Facility in Manhattan, Kansas 2MediVet Biologics Animal Health Secures Additional Laboratory Facility in Manhattan, Kansas 3
... Z. Yang, Varian, Inc. , ... Bisphenol A (BPA) is a primary raw ... and polycarbonate plastic. 4-Nonylphenol (4-NP) is a degradation product of alkylphenol ... is also widely used as an additive in plastics that are ...
... (FRET) between GFP , fusions in lysates of the yeast ... Cary Eclipse , ... Daren J. Fyfe, Ph.D* , ... Clayton campus Victoria 3800, Australia , ...
... , Increased throughput in drug ... N-in-1 experiments. Patented LINAC collision cell technology plays a key role in ... Overview , ... an important impact is in N-in-1 studies (also referred to as cassette ...
Cached Biology Technology:Analysis of Phenolic Estrogen Mimics in River Water by Negative Ion Electrospray LC/MS/MS 2 Monitoring fluorescence resonance energy transfer (FRET) between GFP, fusions in lysates of the yeast Saccharomyces cerevisiae using the , Varian, Cary Eclipse 2 Monitoring fluorescence resonance energy transfer (FRET) between GFP, fusions in lysates of the yeast Saccharomyces cerevisiae using the , Varian, Cary Eclipse 3 Monitoring fluorescence resonance energy transfer (FRET) between GFP, fusions in lysates of the yeast Saccharomyces cerevisiae using the , Varian, Cary Eclipse 4Detection of N-in-1 Experiments: Extending the Range of N Using the API 3000 LC/MS/MS System 2Detection of N-in-1 Experiments: Extending the Range of N Using the API 3000 LC/MS/MS System 3
ATP-binding cassette sub-family D member 4 (Peroxisomal membrane protein 69) (PMP69) (Peroxisomal membrane protein 1-like) (PXMP1-L) (P70R). [Source:Uniprot/SWISSPROT;Acc:O14678] Antigen: Recombi...
... Exonic Evidence Based Oligonucleotide) Genome Set and ... Genome Set contain a collection of open ... expressed exons, allowing interrogation of thousands of ... at Stanford University and UCSF, the sets ...
Rabbit polyclonal to XPC ( Abpromise for all tested applications). Antigen: Synthetic peptide from N-terminus of Human XPC conjugated to a carrier protein Entrez Gene ID: 7508 Swiss ...
Rabbit polyclonal to NIRF ( Abpromise for all tested applications). Antigen: Synthetic peptide derived from residues 186-235 of human NIRF. Entrez Gene ID: 115426 Swiss Protein ID: Q96PU...
Biology Products: