Navigation Links
2 genetic wrongs make a biochemical right
Date:10/20/2013

at a similar approach could be beneficial for kids with this disease."

The next step for Richter and colleagues is to determine which, of the more than 300 mRNAs that both CPEB and FMRP bind to, contribute to Fragile X syndrome and how. They'll also begin looking at small molecules and other avenues that, like the ablation of the CPEB protein, might be able to slow down the synthesis of protein. "There are several small molecules that we know affect the translational apparatus," Richter said. "Some cross the blood/brain barrier, some are toxic, and some are not. We'd like to investigate those."

"This is another, great example of how basic science translates to human disease," said Richter. "If we had started out looking at the human brain, not knowing about the CPEB protein and its role in translational activity, we wouldn't have had any idea where to start or what to look for. But because we started out in the frog, where things are much easier to see, and because more often than not these processes are conserved, we've learned something new and totally unexpected that may have a profound impact on human disease."


'/>"/>

Contact: Jim Fessenden
james.fessenden@umassmed.edu
508-856-2000
University of Massachusetts Medical School
Source:Eurekalert

Page: 1 2 3 4

Related biology news :

1. Babcock Genetics Launches Breed Select Program
2. New genetic discovery could reduce the guesswork in drug dosing
3. What makes us left or right handed? New study rules out strong genetic factors
4. Epigenetic changes observed in blood may point to early stages in Parkinson disease
5. Notre Dame paper sheds light on genetic and physiological basis for metabolic diseases
6. Genetics in Medicine publishes special issue dedicated to genomics in electronic health records
7. JScreen public health initiative launches to fight Jewish genetic diseases
8. Functional genetic variation in humans: Comprehensive map published
9. Better sharing of genetic information in human health
10. African-American study identifies 4 genetic variants associated with blood pressure
11. Early-onset Parkinsons disease linked to genetic deletion
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/30/2014)... HEIGHTS, Ill. (September 30, 2014) People who suffer ... can do to control their asthma besides properly taking ... a new article in the Annals of Allergy, ... American College of Allergy, Asthma and Immunology (ACAAI), asthma ... examining their lifestyle. The woman described in the Annals ...
(Date:9/29/2014)... 2014 -- Plants have a symbiotic relationship with ... extract nutrients and defend against invaders an ... and vegetables. Now, scientist have discovered that plants ... thus ensuring that sprouting plants are colonized from ... Notre Dame, presented their findings today at the ...
(Date:9/29/2014)... should use ventilation when cooking with a gas stove, ... new study showed an association between gas kitchen stove ... "In homes where a gas stove was used without ... than in homes where a gas stove was used ... the College of Public Health and Human Sciences at ...
Breaking Biology News(10 mins):Asthma symptoms kicking up? Check your exposure to air pollution 2Plants prepackage beneficial microbes in their seeds 2Childhood asthma linked to lack of ventilation for gas stoves, OSU study shows 2Childhood asthma linked to lack of ventilation for gas stoves, OSU study shows 3
... people who have a drink or two might be more ... from a University of Florida research group in the ... people 50 or older in the study metabolized alcohol similar ... tests after having moderate amounts of alcohol and did not ...
... seven new species of bamboo coral discovered on a ... Marine National Monument. Six of these species may represent ... classification a genus represents. A genus is a major ... species and below a family. Scientists expect to identify ...
... into children,s health and well-being will help solve global ... The research project, which is headed by Professor Arne ... Sciences at University of Copenhagen and will focus on ... which is based on regional food products. , Overweight ...
Cached Biology News:After a few drinks, older adults more impaired than they think 2After a few drinks, older adults more impaired than they think 3New deep-sea coral discovered on NOAA-supported mission 2Enhanced quality of 'LIFE' through Nordic food 2
(Date:9/30/2014)... (PRWEB) September 30, 2014 Whitehouse ... been chosen by the Parenteral Drug Association (PDA) ... and 19, 2014) on container closure integrity testing. This ... integrity test methods and philosophies detailed in the recently ... Evaluation. The course will span container closure ...
(Date:9/30/2014)... Pittsburgh PA (PRWEB) September 30, 2014 ... Nurses ( IACRN), a non-profit organization based ... Clinical Research Excellence and Safety (ACRES), a ... of a strategic alliance agreement, setting the stage ... is to enhance clinical research quality and safety ...
(Date:9/29/2014)... diagnostics today, with imaging techniques like MRI (magnetic ... (nuclear magnetic resonance) increasing steeply over the last ... and quality still limit these techniques because of ... hyperpolarization, which involves injecting the patient with substances ... distribution and fate of specific molecules in the ...
(Date:9/29/2014)... VIRGINIA BEACH, Va. , Sept. 29, 2014 ... scientists from the fields of cartilage repair, regeneration, ... as attendees from around the world gathered to ... 2014 LifeNet Health Institute of Regenerative Medicine symposium, ... Future Direction . Topics included Orthopedic Biosurgery, Minced ...
Breaking Biology Technology:Whitehouse Laboratories to Partner with PDA for Educational Course on Container Closure Integrity Testing 2Whitehouse Laboratories to Partner with PDA for Educational Course on Container Closure Integrity Testing 3Whitehouse Laboratories to Partner with PDA for Educational Course on Container Closure Integrity Testing 4IACRN and ACRES to Support Clinical Research Nurses 2IACRN and ACRES to Support Clinical Research Nurses 3A safer approach for diagnostic medical imaging 2A safer approach for diagnostic medical imaging 3World Renowned Experts Discuss Future Of Cartilage Regeneration 2World Renowned Experts Discuss Future Of Cartilage Regeneration 3
... DCGN ) today announced that it will host a ... Weisel Partners Healthcare,Conference 2008., The presentation will be ... / 6:30,PM British Summer Time on Wednesday, September 3 ... be accessed through the Investors page on,deCODE,s website, ...
... Abaxis, Inc.,(Nasdaq: ABAX ), a medical products ... Don Wood, Vice President,Operations, and Al Santa Ines, ... Annual West Coast Emerging Growth Institutional Investor Forum ... at the Ritz-Carlton Hotel, San,Francisco, CA., About ...
... Pharmaceuticals,Inc. (Nasdaq: ARNA ) announced today that the ... Biotech Industry Conference on September,4, 2008 at 11:00 a.m. ... Hotel in New York City. Jack Lief, Arena,s President,and ... of the,company, including its clinical development and discovery programs., ...
Cached Biology Technology:deCODE genetics to Webcast Presentation at Thomas Weisel Partners Healthcare Conference 2008 2Arena Pharmaceuticals to Present at the NewsMakers in the Biotech Industry Conference 2Arena Pharmaceuticals to Present at the NewsMakers in the Biotech Industry Conference 3
... system is ideal for routine binary separations. ... Adept CE 4201 UV-Visible variable wavelength detector. ... by the two highly accurate and precise, ... solvent delivery pumps., Chromatograms may be plotted on ...
... A549 cells were cultured in Ham's F12K medium ... log phase of growth. In order to keep ... fixed in acetone-methanol. The cells are arrayed on ... each wells surface specifically treated to enhance cellular ...
CELLine System cultivation flask (for secreted products)...
... K28/86.2, PDZ Domain GenBank Accession ... GST fusion to residues 77-299 of ... pH 7.4, 0.075M NaCl containing 0.05% ... by immunoblot on rat brain microsomal ...
Biology Products: