Navigation Links
'1 pill can kill': Effects of unintentional opioid exposure in young children
Date:8/28/2013

Cincinnati, OH, August 29, 2013 -- Medication poisonings among children are an important public health problem. During 2010-2011, an average of 1500 children under 6 years of age was evaluated in emergency departments each year due to unintentional exposure to buprenorphine. Ingestion of strong opioids, such as buprenorphine, can cause central nervous system depression, respiratory depression, and death in young children. In a new study scheduled for publication in The Journal of Pediatrics, researchers study how young children are gaining access to buprenorphine, as well as the effects of unintentional exposure to its different formulations.

Buprenorphine (or the buprenorphine-naloxone combination form), usually sold as a tablet or film strip, is used to treat adults who are addicted to opioids, such as prescription pain medication and heroin. Tablets typically are dispensed in 30-day supply bottles with child-resistant caps, and film strips are dispensed in single-dose, child-resistant foil packs. Dr. Eric Lavonas and colleagues from the Rocky Mountain Poison and Drug Center, the University of Colorado School of Medicine, the University of Oklahoma, Integris Baptist Medical Center, Degge Group, and Venebio Group studied 2380 cases of unintentional exposure to buprenorphine in any form involving children under 6 years of age. The average age of the children was 2 years. Common effects of buprenorphine exposure were lethargy, respiratory depression, miosis (small pupils), and vomiting. Although most children had good outcomes, 587 children were admitted to the intensive care unit and 4 children died.

The researchers found that children were 3.5 to 8.8 times more likely to accidentally ingest the tablets as have unintentional exposure to film strips; 95% of cases involved tablets. In 57% of the cases, at least one root cause for the exposure was identified: 415 cases involved medication stored in sight, in 110 cases the child acc
'/>"/>

Contact: Becky Lindeman
journal.pediatrics@cchmc.org
513-636-7140
Elsevier Health Sciences
Source:Eurekalert

Page: 1 2

Related biology news :

1. Study adds lung damage to harmful effects of arsenic
2. New tests for determining health and environmental effects of nanomaterials
3. Chemotherapy before radiotherapy for testicular cancer could reduce long-term side-effects
4. Researchers study seleniums effects on horses
5. Study explores effects of review setting on scientific peer review
6. Rapamycin: Limited anti-aging effects
7. Key target responsible for triggering detrimental effects in brain trauma identified
8. Adverse effects of phthalates on ovarian response to IVF
9. Time is of the essence for reducing the long-term effects of iron deficiency
10. Patients use OTC NSAIDs even when they have a high risk of serious side effects
11. Hidden effects of climate change may threaten eelgrass meadows
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/17/2014)... for the first time how bacteria can grow directly ... the opportunity to get tremendous insights into bacteria behavior ... discovered the bacterial growth in chronic lung infections among ... by the immune cells. The researchers discovered the immune ... bacteria, forcing the bacteria to switch to a much ...
(Date:10/16/2014)... of Marine Science have received a 3-year, $392,773 ... the streams and wetlands most vulnerable to sea-level ... governments and citizens conserve these important ecosystems. , ... tidal-marsh observations first gathered by VIMS scientists in ... today,s researchers accurately map the slow but inexorable ...
(Date:10/16/2014)... cultivated efficiently, they are anything but sustainable: environmental ... cultivation is becoming increasingly evident. Despite their disadvantages, ... are regarded as the sole possibility of achieving ... finds Bernhard Schmid, an ecology professor at the ... of agriculture and forestry. After all, a new ...
Breaking Biology News(10 mins):Scientists opens black box on bacterial growth in cystic fibrosis lung infection 2EPA grant will help localities conserve headwater wetlands 2EPA grant will help localities conserve headwater wetlands 3Plant communities produce greater yield than monocultures 2Plant communities produce greater yield than monocultures 3
... the journal Botany is set to showcase ... bringing to the study of pollination biology. The journal,s ... topics that range from the effect of flower structure ... change on pollinator ranges. The issue also includes two ...
... guts of worms are seemingly innocuous bacteria that contribute to ... same bacteria transform from harmless microbes into deadly insecticides. ... University researchers led a study that revealed how a bacteria ... member in the gut microbiome to deadly killer in insect ...
... sensation that your waistband is getting tight. Investigators reporting online ... have now mapped out the signals that travel between ... satiety after eating a protein-rich meal. Understanding this back and ... way for future approaches in the treatment and/or prevention of ...
Cached Biology News:Special issue of Botany showcases CANPOLIN research 2Jekyll and Hyde bacteria aids or kills, depending on chance 2
(Date:10/20/2014)... 20, 2014 Convey Computer , ... team from Iowa State University won first place in ... a Convey HC-2ex, the team’s solution achieved the highest ... than the second place finisher. , Experts from all ... the month long challenge, using a variety of design ...
(Date:10/20/2014)... 20, 2014 /PRNewswire/ - BIOREM Inc. (TSXV: BRM) ("Biorem" or "the ... Q3 orders to $5.8 million and provides a good start to ... North America and one in the ... projects at record levels," said Peter Bruijns , President & ... end of Q3 than they have been for any complete year ...
(Date:10/20/2014)... Oct. 20, 2014  GenVec, Inc. (NASDAQ: GNVC ... , Ph.D., from its board of directors effective on October ... 2003, and served as its chairman from June 2006 to ... Nominating and Corporate Governance and Audit Committees of the board.  ... a decade of dedicated service to GenVec, and its stockholders," ...
(Date:10/20/2014)... 20, 2014 OncLive® ... Cancer Center at Thomas Jefferson University has joined ... the Strategic Alliance Partnership program, the Sidney Kimmel ... to raise awareness of the Center’s cutting-edge research ... projects. Clinicians and other health care professionals from ...
Breaking Biology Technology:Team from Iowa State Wins 2014 MemoCODE Design Contest Using Convey HC-2ex 2Team from Iowa State Wins 2014 MemoCODE Design Contest Using Convey HC-2ex 3Zola P. Horovitz To Retire From GenVec Board 2Sidney Kimmel Cancer Center at Thomas Jefferson University Partners With OncLive 2Sidney Kimmel Cancer Center at Thomas Jefferson University Partners With OncLive 3
... 18 Paragon Bioservices, Inc., a contract research and ... Lilly Global Supplier Award for exceptional performance in support ... be recognized in this manner by such an elite ... guiding principles of quality, excellence and superior customer service ...
... a paper published,today in the online edition of Nature ... academic colleagues from Iceland, Denmark and the,Netherlands present the ... human genome (SNPs) that influence the age of girls ... is influenced by both genetic,and environmental factors, though the ...
... 15 Senetek PLC (OTC Bulletin Board: SNKTY), a ... that target the science of healthy aging, announced that ... is now available by calling 877-SENETEK in the United ... are pleased to provide this service to our investors ...
Cached Biology Technology:deCODE Study Shows Complex Interplay of the Human Biological Clock With Height, Weight and Disease 2deCODE Study Shows Complex Interplay of the Human Biological Clock With Height, Weight and Disease 3deCODE Study Shows Complex Interplay of the Human Biological Clock With Height, Weight and Disease 4Senetek PLC Investor Hotline Goes Live 2
... offers precision beveling of micropipette ... The unique abrasive plate drive ... greater control of the beveling ... very rapidly and produces consistent ...
... The EC570-90 is a compact, lightweight, high current ... volts or 2500 milliamps. It is an excellent ... submarine gels. It is also ideal for all ... can be set to automatically end a run ...
... Grade Thrombin is a highly purified preparation ... with appropriate vectors. The preparation is functionally ... is free of detectable contaminating proteases. Prepared ... by certified tests to be negative for ...
Acetate Plate Sealers 100/Box...
Biology Products: