Navigation Links
Nicotinamide adenine dinucleotide


Nicotinamide adenine dinucleotide (NAD) and nicotinamide adenine dinucleotide phosphate (NADP) are two important coenzymes found in cells. NADH is the reduced form and NAD+ is the oxidized form of NAD.

NAD is used extensively in glycolysis and the citric acid cycle of cellular respiration. It forms NADP with the addition of a phosphate group to the 2' position of the nucleotide through an ester linkage. NADP is produced in the preliminary cycles of photosynthesis, and is used in the later Calvin cycle of photosynthesis. It is used in many other anabolic reactions in various organisms as well.

MH2 + NAD+ → NADH + H+ + M: + energy, where M is a metabolite.

Two hydrogen ions (a hydride ion and an H+ ion) are transferred from the metabolite. Two electrons are transferred to the positively charged nitrogen, and one hydrogen attaches to the carbon atom opposite to the nitrogen.

The human body synthesises NAD from the vitamin niacin in the form of nicotinic acid or nicotinamide.

See also

References and external links


'"/>


(Date:7/1/2020)... ... July 01, 2020 , ... ... completed the purchase of Teva-Takeda Pharmaceuticals’ packaging facility in Minakuchi, located in the ... clinical supply facility located in Kakegawa, the new 60,000-square-foot facility will provide customers ...
(Date:6/28/2020)... , ... June 25, 2020 ... ... enterprise software solutions for biopharmaceutical R&D, today announced that it has entered ... innovative, full-length multispecific antibodies (Multiclonics®), to support their translational and clinical research ...
(Date:6/25/2020)... ... June 24, 2020 , ... ... software and software-driven clinical data services that accelerate drug development, is collaborating with ... an XPO1 inhibitor, in hospitalized patients with severe COVID-19. This is the first ...
Breaking Biology News(10 mins):
Other biology definition